Membrane fusion.
Membrane fusion.
复制标题
膜融合。
DOI：
10.1007/978-1-4899-1698-3_5
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发表时间：
1985
影响因子：
--
通讯作者：
Düzgüneş,N
中科院分区：
文献类型：
--
作者：
Düzgüneş,N
膜融合是一个重要的生物学过程，在各种各样的细胞内和细胞间事件中观察到。关于它的分子机制知之甚少，在生物系统中控制它的因素也很少。即使在详尽研究的现象，如神经递质的释放，或刺激分泌耦合一般，分子事件的先决条件之间的分泌囊泡和质膜膜融合的启动还没有得到很好的理解。在这篇文章中，我们将回顾生物膜和模型膜系统中膜融合机制的研究，并试图从研究的不同膜融合系统中找出这一过程的关键要素。然而，我们将强调在这些系统中可以诱导膜融合的各种条件。
Membrane fusion is an important biological process that is observed in a wide variety of intra- and intercellular events. Little is known about its molecular mechanisms and few of the factors which control it in biological systems are known. Even in exhaustively studied phenomena such as neurotransmitter release, or stimulus-secretion coupling in general, the molecular events that are prerequisites for the initiation of membrane fusion between secretory vesicles and the plasma membrane are not well understood. In this communication we shall review studies on the mechanisms of membrane fusion in biological membranes and in model membrane systems and attempt to bring out the critical elements of this process from among the diverse membrane fusion systems studied. We shall nevertheless emphasize the large variety of conditions under which membrane fusion can be induced in these systems.