Laser photocoagulation for choroidal new vessel membrane complicating age-related macular degeneration associated with pigment epithelial detachment.

Laser photocoagulation for choroidal new vessel membrane complicating age-related macular degeneration associated with pigment epithelial detachment.
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激光光凝治疗脉络膜新生血管膜,使与色素上皮脱离相关的年龄相关性黄斑变性复杂化。

DOI:
10.1097/00006982-198808020-00006
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发表时间:
1988
期刊:
Retina
影响因子:
--
通讯作者:
L. Singerman
L. Singerman
中科院分区:
--
文献类型:
--
作者:
L. Singerman

文献摘要

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我们研究了124只连续接受激光光凝治疗与色素上皮脱离(PED)相关的脉络膜新血管膜(NVM)的眼睛。在许多情况下,NVM的程度是不确定的。我们认为不是所有的病例都是在中央凹下但可能在一个亚组的病例中是在中央凹下。在平均16个月的随访中,53%接受治疗的眼睛视力稳定或改善。氩气治疗和氪气治疗的结果没有差异。在荧光素血管造影的基础上,我们将86只眼睛分为四个非排他组。68%的中央凹旁或中央凹外PED患者、48%的中央凹下PED患者、76%的中央凹旁或中央凹外NVM患者和50%的可能中央凹下NVM患者视力稳定或改善。一项随机临床试验的激光光凝治疗NVM在PED是指和必要的。在黄斑光凝研究的支持下,目前正在进行一项试点研究,以确定这种试验的可行性并制定一项方案。
We studied 124 consecutive eyes that had laser photocoagulation for choroidal new vessel membranes (NVM) associated with pigment epithelial detachment (PED). In many cases, the extent of the NVM was uncertain. We thought it was not subfoveal in all cases but it possibly may have been subfoveal in one subgroup of cases. With a mean follow-up of 16 months, vision was stable or improved in 53% of the treated eyes. There was no difference in outcome between argon-treated and krypton-treated eyes. On the basis of fluorescein angiograms, we classified 86 of the eyes into four nonexclusive groups. Vision was stable or improved in 68% of eyes with juxtafoveal or extrafoveal PED, 48% with subfoveal PED, 76% with juxtafoveal or extrafoveal NVM, and 50% of eyes with possibly subfoveal NVM. A randomized clinical trial of laser photocoagulation for NVM in PED is both indicated and warranted. A pilot study under the auspices of the Macular Photocoagulation Study is now under way to determine the feasibility of and develop a protocol for such a trial.