BiNGO: a Cytoscape plugin to assess overrepresentation of Gene Ontology categories in Biological Networks
BiNGO: a Cytoscape plugin to assess overrepresentation of Gene Ontology categories in Biological Networks
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DOI：
10.1093/bioinformatics/bti551
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发表时间：
2005-08-15
期刊：
影响因子：
5.8
通讯作者：
Kuiper, M
中科院分区：
文献类型：
--
作者：
Maere, S;Heymans, K;Kuiper, M
Biological Networks Gene Ontology tool（BiNGO）是一个开源的Java工具，用于确定哪些基因本体（GO）术语在一组基因中显着过度表达。BiNGO既可以用于基因列表，粘贴为文本，也可以交互式地用于Cytoscape中可视化的生物网络的子图。BiNGO将测试基因组的主要功能主题映射到GO层次结构上，并利用Cytoscape的多功能可视化环境来生成结果的直观和可定制的视觉表示。
The Biological Networks Gene Ontology tool (BiNGO) is an open-source Java tool to determine which Gene Ontology (GO) terms are significantly overrepresented in a set of genes. BiNGO can be used either on a list of genes, pasted as text, or interactively on subgraphs of biological networks visualized in Cytoscape. BiNGO maps the predominant functional themes of the tested gene set on the GO hierarchy, and takes advantage of Cytoscape's versatile visualization environment to produce an intuitive and customizable visual representation of the results.