Janus nanoparticles with both faces selectively functionalized for click chemistry
Janus nanoparticles with both faces selectively functionalized for click chemistry
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DOI：
10.1039/c4py00085d
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发表时间：
2014-06
影响因子：
4.6
通讯作者：
R. H. Staff;Jochen Willersinn;A. Musyanovych;K. Landfester;D. Crespy
中科院分区：
文献类型：
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作者：
R. H. Staff;Jochen Willersinn;A. Musyanovych;K. Landfester;D. Crespy
在水中制备了具有叠氮官能团化和炔基功能化的Janus纳米粒子。可以通过控制用于产生Janus粒子的聚合物中的官能团密度来调节官能团的表面密度。控制是通过自由基聚合和原子转移自由基聚合(ATRP)来实现的，其中功能单体的比例是通过自由基聚合和原子转移自由基聚合来实现的。此外，还开发了试剂和方法来定量Janus颗粒表面的炔基和叠氮基。因此，这些团体的活动也得到了证明。
Janus nanoparticles presenting one face functionalized with azide and one face functionalized with alkyne groups were prepared in water. The surface density of the functional groups could be adjusted by controlling the functional group density in the polymers used to generate the Janus particles. The control was achieved by the preparation of copolymers in which the ratio of the functional monomer was varied by free-radical polymerization and by the use of atom transfer radical polymerization (ATRP) with functional initiators. Furthermore, reagents and methods were developed to quantify the alkyne and azide groups on the surface of the Janus particles. Thus, the activity of the groups was also proven.