Metarhodopsin control by arrestin, light-filtering screening pigments, and visual pigment turnover in invertebrate microvillar photoreceptors.
Metarhodopsin control by arrestin, light-filtering screening pigments, and visual pigment turnover in invertebrate microvillar photoreceptors.
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DOI：
10.1007/s00359-010-0604-7
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发表时间：
2011-03
影响因子：
2.1
通讯作者：
Hardie, Roger C.
中科院分区：
文献类型：
--
作者：
Stavenga, Doekele G.;Hardie, Roger C.
大多数无脊椎动物光感受器的视觉色素具有两种热稳定的光可相互转换状态，即基态视紫红质和光激活的变视紫红质，其触发光转导级联直到它与视紫红质结合。光平衡中两种状态的比率由它们的吸收光谱和照明的有效光谱分布决定。计算表明，由于蓝绿色视紫红质、吸收橙色的变视紫红质和红色透明屏蔽颜料的结合，在正常的昼间环境中，果蝇光感受器中的变视紫红质水平保持在约 35% 以下。缓慢的变视紫质降解和视紫红质再生过程进一步促进视觉色素的维持。在大多数昆虫的眼睛中，大多数光感受器都含有吸收绿色的视紫红质和吸收蓝色的变视紫红质，预计自然光源在高强度下会产生大于 60% 的变视紫质水平。然而，快速的变视紫红质衰减和视紫红质再生在控制绿色受体中的变视紫红质方面也发挥着重要作用，导致低光强度下视紫红质含量较高，而亮光下视色素总含量减少。视色素-抑制蛋白循环的简单模型用于说明视色素群体状态对光强度、抑制蛋白水平和色素周转的依赖性。
The visual pigments of most invertebrate photoreceptors have two thermostable photo-interconvertible states, the ground state rhodopsin and photo-activated metarhodopsin, which triggers the phototransduction cascade until it binds arrestin. The ratio of the two states in photoequilibrium is determined by their absorbance spectra and the effective spectral distribution of illumination. Calculations indicate that metarhodopsin levels in fly photoreceptors are maintained below ~35% in normal diurnal environments, due to the combination of a blue-green rhodopsin, an orange-absorbing metarhodopsin and red transparent screening pigments. Slow metarhodopsin degradation and rhodopsin regeneration processes further subserve visual pigment maintenance. In most insect eyes, where the majority of photoreceptors have green-absorbing rhodopsins and blue-absorbing metarhodopsins, natural illuminants are predicted to create metarhodopsin levels greater than 60% at high intensities. However, fast metarhodopsin decay and rhodopsin regeneration also play an important role in controlling metarhodopsin in green receptors, resulting in a high rhodopsin content at low light intensities and a reduced overall visual pigment content in bright light. A simple model for the visual pigment–arrestin cycle is used to illustrate the dependence of the visual pigment population states on light intensity, arrestin levels and pigment turnover.
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DOI：
10.1007/bf00709805
发表时间：
1975-01-01
期刊：
JOURNAL OF COMPARATIVE PHYSIOLOGY
影响因子：
--
作者：
MINKE, B;WU, CF;PAK, WL
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PAK, WL
DOI：
10.1007/bf00697773
发表时间：
1972-01-01
期刊：
Journal of Comparative Physiology
影响因子：
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STRUWE G
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DOI：
10.1007/s00359-009-0489-5
发表时间：
2010-01
影响因子：
2.1
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Belusic, Gregor;Pirih, Primoz;Stavenga, Doekele G.
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DOI：
10.1007/bf00535444
发表时间：
1979-01-01
期刊：
BIOPHYSICS OF STRUCTURE AND MECHANISM
影响因子：
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RAZMJOO, S
DOI：
10.1007/bf00535813
发表时间：
1977-01-01
期刊：
BIOPHYSICS OF STRUCTURE AND MECHANISM
影响因子：
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作者：
HAMDORF, K;RAZMJOO, S
通讯作者：
RAZMJOO, S