Antiparasitic activities of medicinal plants used in Ivory Coast
Antiparasitic activities of medicinal plants used in Ivory Coast
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DOI：
10.1016/j.jep.2003.09.029
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发表时间：
2004-01-01
影响因子：
5.4
通讯作者：
Hocquemiller, R
中科院分区：
文献类型：
--
作者：
Okpekon, T;Yolou, S;Hocquemiller, R
在对科特迪瓦使用的抗寄生虫药用植物的民族药理学调查中，鉴定和收集了17种植物。在体外抗寄生虫药物筛选中，对不同部位的极性、非极性和生物碱提取物进行了评价。测定了抗疟、利什曼尼虫、锥虫、驱虫和抗疥疮活性。在所选植物中，对恶性疟原虫有较强的抗虫活性的植物有平栎和青尾草。与其他15种植物一样，选择性地用于治疗锥虫病的无底洞草也显示出有趣的锥虫活性。其中10种活性菌有除螨活性，2种对螨有除螨活性，分别为阿夫扎利乌氏菌和肉芽单念珠菌。2003爱思唯尔爱尔兰有限公司版权所有。
During an ethnopharmacological survey of antiparasitic medicinal plants used in Ivory Coast, 17 plants were identified and collected. Polar, non-polar and alkaloidic extracts of various parts of these species were evaluated in vitro in an antiparasitic drug screening. Antimalarial, leishmanicidal, trypanocidal, antihelminthiasis and antiscabies activities were determined. Among the selected plants, Anogeissus leiocarpus and Terminalia glaucescens were strongly active against Plasmodium falciparum. Lawsonia inermis, selectively prescribed against trypanosomiasis shows interesting trypanocidal activities as did other 15 plants. Anthelmintic activities were found for 10 active species and 2 species (Uvaria afzelli and Monodora myristica) were actives against mites. (C) 2003 Elsevier Ireland Ltd. All rights reserved.