Acanthamoeba meningoencephalitis in a patient with AIDS.
Acanthamoeba meningoencephalitis in a patient with AIDS.
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艾滋病患者的棘阿米巴脑膜脑炎。
DOI：
10.1093/infdis/155.1.130
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发表时间：
1987
期刊：
影响因子：
--
通讯作者：
Visvesvara,GS
中科院分区：
文献类型：
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作者：
Wiley,CA;Safrin,RE;Davis,CE;Lampert,PW;Braude,AI;Martinez,AJ;Visvesvara,GS
艾滋病患者易感染许多微生物，这些微生物要么是人类感染的罕见原因，要么是致病性低。这些患者的中枢神经系统是感染的常见部位[1]，病原体的确认通常只能通过脑活检来确定。本报告的目的是记录致命的脑膜脑炎引起的阿米巴culbertsoni在艾滋病患者。A.免疫功能低下小鼠的实验性感染反映了该免疫功能低下患者中CNS的Culbertsoni感染。
Patients with AIDS are susceptible to infections with many microorganisms that are either uncommon causes of human infection or that are of low pathogenicity. The CNS of these patients is a frequent site of infection [1], and iden-tification the etiologic agent is often established only by brain biopsy. The purpose of this report is to document fatal meningoencephalitis caused by Acanthamoeba culbertsoni in a patient with AIDS. The peculiar tropism of A. culbertsoni for the CNS in this immunocompromised patient was reflected by experimental infections of immunocompromised mice.