Growth charts for children with Down syndrome: 1 month to 18 years of age.

Growth charts for children with Down syndrome: 1 month to 18 years of age.
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唐氏综合症儿童生长曲线图:1 个月至 18 岁。

DOI:
10.1542/peds.81.1.102
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发表时间:
1988
期刊:
影响因子:
8
通讯作者:
R. Reed
R. Reed
中科院分区:
医学2区
文献类型:
--
作者:
C. Cronk;A. Crocker;S. Pueschel;A. M. Shea;E. Zackai;Gary Pickens;R. Reed

文献摘要

被引文献

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根据对730名儿童的4650项观察,给出了两个年龄区间(1至36个月和2至18岁)的身高和体重评估百分位图,反映了家庭养育的唐氏综合症儿童的预期缺陷尺寸和生长速度。数据汇集并用于估计五个百分位,并使用灵活的数学函数进行平滑处理。这些数据证实了其他关于唐氏综合症儿童生长的研究,表明在整个生长时期生长速度都有缺陷,但在婴儿期和青春期最为明显。本研究样本中的唐氏综合症患儿在整个生长时期的各个年龄段均高于机构样本中的唐氏综合症患儿。患有中度或重度先天性心脏病的儿童比没有或只有轻度疾病的儿童平均矮1.5至2.0厘米,体重轻约1公斤。平均体重和体重除以身高的平方表明,患有唐氏综合症的儿童在婴儿期后期和整个成长阶段都有超重的趋势。
Centile charts for assessment of stature and weight reflecting expected deficient size and growth rate of home-reared children with Down syndrome are presented for two age intervals, 1 to 36 months and 2 to 18 years, based on 4650 observations on 730 children. Data were pooled and used to estimate five centiles which were smoothed using a flexible mathematical function. These data corroborate other studies of growth in children with Down syndrome demonstrating deficient growth rate throughout the growing period, but most marked in infancy and again at adolescence. Children with Down syndrome in the present sample were taller than those from institutionalized samples at all ages throughout the growing period. Children with moderate or severe congenital heart disease on average were 1.5 to 2.0 cm shorter and about 1 kg lighter than those without or with only mild disease. Mean weight and weight divided by stature squared show that children with Down syndrome have a tendency to be overweight beginning in late infancy and throughout the remainder of the growing years.