Dietary fat is associated with metabolic syndrome in Japanese Brazilians
Dietary fat is associated with metabolic syndrome in Japanese Brazilians
复制标题
DOI：
10.2337/diacare.28.7.1779
复制
发表时间：
2005-07-01
期刊：
影响因子：
16.2
通讯作者：
Ferreira, SRG
中科院分区：
文献类型：
--
作者：
Freire, RD;Cardoso, MA;Ferreira, SRG
目的-本研究的目的是研究与代谢综合征的营养摄入量在高风险的代谢abnormal.RESEARCH设计和方法-在一个基于人口的研究日本巴西人的年龄：30岁，412名男性和465名女性进行了研究的日本后裔人口的关联。代谢综合征的诊断是基于为亚洲人修改的国家胆固醇教育计划标准。食物摄入量通过一个有效的食物频率问卷进行评估。（55.7 +/- 12.7岁和54.4 +/- 11.9岁）和49%（95% CI 44.8-54.6）和43%（38.4-47.6）分别患有代谢综合征，正如预期的那样，代谢综合征受试者亚组的临床参数不太有利。有代谢综合征的男性比无代谢综合征的男性胆固醇摄入量高（233.2 +/- 116.3 vs. 211.7 +/- 5.8 g/d，P < 0.05），碳水化合物摄入量低（288.5 +/- 45.8 vs. 300.1 +/- 39.8 g/d，P < 0.001），但在女性中没有观察到差异。在调整性别、年龄、吸烟、教育水平、世代、体力活动、总能量和膳食纤维摄入量后，检测到代谢综合征与总脂肪摄入量之间存在正相关。总脂肪消耗量最高五分位数人群与最低五分位数人群比较，代谢综合征的优势比（OR）为5.0（[95% CI 1.58-16.00] P < 0.005）。相反，亚油酸摄入量与代谢综合征呈负相关（OR 0.50 [95% CI 0.26-0.981 P < 0.05）。考虑到食物组，调整后，只有油炸食品的摄入量被证明是与代谢综合征的风险增加。结论-尽管这种研究设计的局限性，在调查因果关系，我们的研究结果有利于假设，饮食中的总脂肪可能会增加，而亚油酸的摄入量可能会降低在巴西生活的日本后裔的代谢综合征的风险。
OBJECTIVE - The aim of this study was to examine the association of nutrient intakes with metabolic syndrome in a Japanese descendant population at high risk for metabolic abnormalities.RESEARCH DESIGN AND METHODS - in a population-based study of Japanese Brazilians aged :30 years, 412 men and 465 women were studied. The diagnosis of metabolic syndrome was based on the National Cholesterol Education Program criteria modified for Asians. Food intake was assessed by a validated food frequency questionnaire.RESULTS - Men and women showed similar mean ages (55.7 +/- 12.7 and 54.4 +/- 11.9 years) and 49% (95% Cl 44.8-54.6) and 43% (38.4-47.6) had metabolic syndrome, respectively, As expected, clinical parameters were less favorable in the subset of subjects with metabolic syndrome. Men with metabolic syndrome showed higher cholesterol (233.2 +/- 116.3 vs. 211.7 +/- 5.8 g/day, P < 0.05) and lower carbohydrate (288.5 +/- 45.8 vs. 300.1 +/- 39.8 g/day, P < 0.001) intakes than those Without metabolic syndrome, but no difference was observed among the women. After adjusting for sex, age, smoking, education level, generation, physical activity, total energy, and dietary fiber intake, a positive association between Metabolic syndrome and total fat intake was detected. Comparing people in the highest quintile of total fat consumption with those in the lowest quintile, odds ratio (OR) of metabolic syndrome was 5.0 ([95% Cl 1.58-16.00] P < 0.005). In contrast, linoleic acid intake was inversely associated with metabolic syndrome (OR 0.50 [95% Cl 0.26-0.981 P < 0.05). Considering food groups, after adjustments only fried food intake was shown to be associated with increased risk of metabolic syndrome.CONCLUSIONS- Despite the limitation of such a study design in investigating cause-effect relationships, our findings favor the hypothesis that dietary total fat may increase whereas linoleic acid intake may reduce the risk of metabolic syndrome in Japanese descendants living in Brazil.