THE MEDIAL FOREBRAIN-BUNDLE OF THE RAT .1. GENERAL INTRODUCTION
THE MEDIAL FOREBRAIN-BUNDLE OF THE RAT .1. GENERAL INTRODUCTION
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DOI：
10.1002/cne.902060106
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发表时间：
1982-01-01
影响因子：
2.5
通讯作者：
VEENING, JG
中科院分区：
文献类型：
--
作者：
NIEUWENHUYS, R;GEERAEDTS, LMG;VEENING, JG
本文是对大鼠内侧前脑束（MFB）的结构、组成及其与床核、下丘脑外侧区的关系的系列研究之一。本文的第一部分包括一个广泛的文献回顾MFB从它的发现Ganser在1882年到现在。这一审查的基础上，我们目前的知识的组织MFB，这是本文的第二部分提出的评估。尽管丰富的信息，构成MFB的轴突的起源和终止的网站，令人惊讶的是很少有人注意到束本身，其地形边界，其纤维组成，或其组成成分的空间排列。这些功能的MFB，因为它延伸通过外侧视前区和外侧下丘脑区已在正常的克鲁弗-巴雷拉和Bodian染色的材料进行了分析。根据这些分析，MFB和周围一些结构的详细地图集已经准备好了。本图集是本文的第三部分，它从视前区外侧连续体和下丘脑外侧连续体等距离的10个水平上，详细地描述了内侧前脑束的形态和结构。端脑内侧束（Fasciculus medialis telephali，MFB）是脊椎动物前脑中的一个重要纤维系统。在哺乳动物中，它代表边缘前脑-中脑连续体的中央纵向通路。从嗅结节吻侧延伸到中脑被盖腹内侧部尾侧，这主要是细纤维束是最清楚的定义，因为它穿过外侧视前区和外侧下丘脑区。虽然丰富的信息是可利用的各种起源和终止的轴突，构成MFB的网站，仔细审查的文献显示，相对较少的注意已经支付给组织的束本身，它的边界，它的纤维组成，或其组成部分的空间排列。本文是对大鼠MFB结构和组成的一系列研究的第一篇。在第一节中的相关文献将进行审查;在第二节中，目前的知识束进行评估;和在最后一节的主要轨迹的MFB，即，部分延伸通过外侧preopticohypothalamic连续体，将被描述。该描述基于正常的Kluver-Barrera和Bodian染色材料。随附的插图共同构成了一个地图集，将作为以后研究的基础。
This paper is the first of a projected series of studies on the structure and composition of the medial forebrain bundle (MFB) of the rat and the relations of this fiber system to its bed nucleus, the lateral hypothalamic area. The first part of the paper comprises an extensive review of literature on the MFB from its discovery by Ganser in 1882 to the present. This review serves as the basis for an evaluation of our present-day knowledge of the organization of the MFB, which is presented in the second part of this paper. Despite the wealth of information available on the origins and sites of termination of the axons that constitute the MFB, surprisingly little attention has been given to the bundle itself, to its topographic boundaries, its fiber composition, or to the spatial arrangement of its constituent components. These features of the MFB as it extends through the lateral preoptic and lateral hypothalamic areas have been analyzed in normal Kluver-Barrera-and Bodian-stained material. From this analysis, a detailed atlas of the MFB and some of the surrounding structures has been prepared. This atlas, which forms the third section of this paper, illustrates the appearance and organization of the MFB at ten equidistant levels through the lateral preoptic and lateral hypothalamic continuum.The fasciculus medialis telencephali or medial forebrain bundle (MFB) is an important fiber system in the forebrain of all groups of vertebrates. In mammals it represents the central longitudinal pathway of the limbic forebrain-midbrain continuum. Extending from the tuberculum olfactorium rostrally to the ventromedial part of the tegmentum mesencephali caudally, this mostly thin-fibered bundle is most clearly defined as it traverses the lateral preoptic and lateral hypothalamic areas. Although a wealth of information is available on the various origins and sites of termination of the axons that constitute the MFB, careful review of the literature reveals that relatively little attention has been paid to the organization of the bundle itself, to its boundaries, to its fiber composition, or to the spatial arrangement of its constituent components. The present paper is the first of a series of studies on the structure and composition of the MFB in the rat. In the first section the pertinent literature will be reviewed; in the second section current knowledge of the bundle is evaluated; and in the final section the main trajectory of the MFB, ie, the part extending through the lateral preopticohypothalamic continuum, will be described. This description is based on normal Kluver-Barrera-and Bodian-stained material. The accompanying illustrations together constitute an atlas, which will serve as the basis for the later studies.