Antenatal immunisation intentions of expectant parents: Relationship to immunisation timeliness during infancy

Antenatal immunisation intentions of expectant parents: Relationship to immunisation timeliness during infancy
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DOI:
10.1016/j.vaccine.2016.01.048
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发表时间:
2016-03-08
期刊:
影响因子:
5.5
通讯作者:
Morton, Susan M. B.
Morton, Susan M. B.
中科院分区:
医学3区
文献类型:
--
作者:
Grant, Cameron C.;Chen, Mei-Hua;Morton, Susan M. B.

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背景:大多数妇女在怀孕期间决定婴儿免疫接种。然而,我们对他们伴侣的免疫意图了解有限。我们的目的是描述什么孕妇和他们的合作伙伴打算为他们未来的孩子的免疫接种,并确定父母的意图和随后的及时性之间的关联婴儿immunosisation.Methods:我们招募了一个队列的新西兰(NZ)孕妇预计提供2009年4月至2010年3月。该队列包括11%的新生儿在新西兰在招募期间,是generalisable到全国出生coherent.We独立完成产前采访的母亲和合作伙伴。我们从国家免疫登记处确定了免疫接种接收,并将及时免疫定义为在到期日30天内接受所有疫苗(计划在6周,3个月和5个月)。我们使用调整后的比值比(OR)和95%置信区间(CI)描述了免疫接种意图与及时性的独立关联。结果:在6172名妇女中,5014(81%)人打算进行完全免疫接种,245(4%)人打算进行部分免疫接种,140(2%)人没有免疫接种,773(13%)人尚未决定。在4152名伴侣中,2942名(71%)打算进行完全免疫,208名(5%)打算进行部分免疫,83名(2%)不打算进行免疫,921名(22%)尚未决定。母亲和伴侣之间的协议是中度(Kappa = 0.42)。及时免疫发生在70%的婴儿。独立于其伴侣的意图,决定完全免疫的孕妇的婴儿更有可能按时免疫(OR = 7.65,95%CI:4.87 - 12.18)。独立的未来母亲的意图,婴儿的合作伙伴谁决定后,充分免疫接种更有可能及时免疫接种(OR = 3.33,95% CI:2.29 - 4.84)。结论:在怀孕期间,大多数未来的父母打算充分免疫他们的孩子,但是,更多的合作伙伴比母亲仍然没有决定免疫接种。未来母亲和未来父亲的意图都与婴儿接种疫苗的及时性独立相关。(C)2016爱思唯尔有限公司版权所有
Background: Most women decide about infant immunisation during pregnancy. However, we have limited knowledge of the immunisation intentions of their partners. We aimed to describe what pregnant women and their partners intended for their future child's immunisations, and to identify associations between parental intentions and the subsequent timeliness of infant immunisation.Methods: We recruited a cohort of pregnant New Zealand (NZ) women expecting to deliver between April 2009 and March 2010. The cohort included 11% of births in NZ during the recruitment period and was generalisable to the national birth cohort.We completed antenatal interviews independently with mothers and partners. We determined immunisation receipt from the National Immunisation Register and defined timely immunisation as receiving all vaccines (scheduled at 6-weeks, 3- and 5-months) within 30 days of their due date. We described independent associations of immunisation intentions with timeliness using adjusted odds ratios (OR) and 95% confidence intervals (CI).Results: Of 6172 women, 5014 (81%) intended full immunisation, 245 (4%) partial immunisation, 140 (2%) no immunisation and 773 (13%) were undecided. Of 4152 partners, 2942 (71%) intended full immunisation, 208 (5%) partial immunisation, 83 (2%) no immunisation and 921 (22%) were undecided. Agreement between mothers and partners was moderate (Kappa = 0.42).Timely immunisation occurred in 70% of infants. Independent of their partner's intentions, infants of pregnant women who decided upon full immunisation were more likely to be immunised on time (OR = 7.65, 95% CI: 4.87 - 12.18). Independent of the future mother's intentions, infants of partners who had decided upon full immunisations were more likely to be immunised on time (OR = 3.33, 95% CI: 2.29 - 4.84).Conclusions: During pregnancy, most future parents intend to fully immunise their child; however, more partners than mothers remain undecided about immunisation. Both future mothers' and future fathers' intentions are independently associated with the timeliness of their infant's immunisations. (C) 2016 Elsevier Ltd. All rights reserved.