Trust in the attending rheumatologist, health-related hope and medication adherence among Japanese systemic lupus erythematosus patients
Trust in the attending rheumatologist, health-related hope and medication adherence among Japanese systemic lupus erythematosus patients
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日本系统性红斑狼疮患者对主治风湿病专家的信任、健康相关的希望和药物依从性
DOI：
10.1093/rheumatology/keac565
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发表时间：
2022
期刊：
影响因子：
5.5
通讯作者：
Yajima Nobuyuki
中科院分区：
文献类型：
--
作者：
Kurita Noriaki;Oguro Nao;Miyawaki Yoshia;Hidekawa Chiharu;Sakurai Natsuki;Ichikawa Takanori;Ishikawa Yuichi;Hayashi Keigo;Shidahara Kenta;Kishida Dai;Yoshimi Ryusuke;Sada Ken-ei;Shimojima Yasuhiro;Yajima Nobuyuki
目的 SLE 患者服药依从性差是与不良后果相关的一个关键问题。这项研究调查了与医生种族匹配的日本 SLE 患者对医生的信任与目标导向思维、希望和药物依从性之间的关系。方法这项横断面研究在五个学术中心的风湿病门诊进行。接受口服药物治疗的系统性红斑狼疮患者也被纳入其中。主要暴露的是对医生的信任度，通过日本版维克森林医生信任量表的 5 项和健康相关希望量表的 18 项来衡量，每项得分范围为 0 至 100 分。药物依从性使用 12 项药物依从性量表进行测量，分数范围为 5 至 60 分。在调整人口统计、社会经济状况、疾病活动性、疾病持续时间、基本健康素养、抑郁、药物变量、经历的不良反应以及对狼疮药物的担忧后，创建了一般线性模型。结果总共纳入了 373 名 SLE 患者。患者的平均年龄为46.4岁；其中，女性 329 人（88.2%）。对医生的信任（每增加 10 分：0.86，95% CI 0.49，1.22）和健康相关希望评分（每增加 10 分：0.66，95% CI 0.35，0.97）都与更好的药物依从性相关。系统性红斑狼疮。
ObjectivePoor medication adherence among patients with SLE is a critical problem associated with adverse outcomes. This study examined the relationship between trust in one’s physician and goal-oriented thinking, hope and medication adherence among Japanese patients with SLE who were ethnically matched to their physicians.MethodsThis cross-sectional study was conducted in the rheumatology outpatient clinics at five academic centres. Patients with SLE who were prescribed oral medications were included. The main exposures were trust in one’s physician measured via the 5-item Japanese version of the Wake Forest Physician Trust Scale and the 18-item Health-related Hope Scale, with each score ranging from 0 to 100 points. Medication adherence was measured using the 12-item Medication Adherence Scale with scores ranging from 5 to 60 points. A general linear model was created after adjusting for demographics, socioeconomic status, disease activity, disease duration, basic health literacy, depression, medication variables, experiencing adverse effects and concerns regarding lupus medications.ResultsAltogether, 373 patients with SLE were included. The mean age of the patients was 46.4 years; among them, 329 (88.2%) were women. Both trust in one’s physician (per 10-point increase: 0.86, 95% CI 0.49, 1.22) and the Health-related Hope score (per 10-point increase: 0.66, 95% CI 0.35, 0.97) were associated with better medication adherence.ConclusionsThis study demonstrated that patients’ health-related hope and trust in their rheumatologist were both associated with better medication adherence in SLE.