Resection of hepatocellular carcinomas
Resection of hepatocellular carcinomas
复制标题
肝细胞癌切除术
DOI：
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发表时间：
1990
期刊：
影响因子：
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通讯作者：
M. Dellepiane
中科院分区：
文献类型：
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作者：
D. Franco;L. Capussotti;C. Smadja;H. Bouzari;J. Meakins;F. Kemeny;D. Grange;M. Dellepiane
本研究旨在确定欧洲肝硬化患者肝细胞癌切除术的结果，使用与东方相同的标准来检测、手术处理和肿瘤病理。72例患者进行了肝脏切除术。1年和3年生存率分别为68%和51%。Child's/Pugh's A级患者的生存率明显高于B-C级患者。与浸润性肿瘤患者相比，厚包被性肿瘤患者的生存时间更长，肿瘤复发率也明显较低。A类厚包膜肝细胞癌患者3年生存率为77%。肿瘤的大小或症状的存在与生存没有关系。这些数据表明，通过切除欧洲肝硬化患者的肝细胞癌可以获得良好的结果。厚包膜肿瘤和适当的肝功能是低复发和高生存率的主要决定因素。本系列的临床结果与东方报道的结果相似。
Abstract This study was undertaken to determine the results of resection of hepatocellular carcinoma in cirrhotic patients in Europe, using the same criteria as in the Orient for detection, surgical management, and pathology of the tumors. Seventy-two patients had a liver resection. One- and 3-yr survival rates were 68% and 51%, respectively. Survival rate was significantly higher in Child's/Pugh's class A than in class B-C patients. Patients with a thickly encapsulated tumor lived longer than those with an infiltrating tumor and had in addition a significantly lower incidence of cancer recurrence. Class A patients with a thickly encapsulated hepatocellular carcinoma had a 77% 3-year survival rate. There was no relation between the size of the tumor or the presence of symptoms and survival. These data suggest that good results can be achieved by resection of hepatocellular carcinomas in European cirrhotic patients. A thickly encapsulated tumor and an adequate liver function are the main determinants of low cancer recurrence and high survival. The clinical results in this series are similar to those reported from the Orient.