PH ADJUSTMENT OF MEPIVACAINE DECREASES THE INCIDENCE OF TOURNIQUET PAIN DURING AXILLARY BRACHIAL-PLEXUS ANESTHESIA
PH ADJUSTMENT OF MEPIVACAINE DECREASES THE INCIDENCE OF TOURNIQUET PAIN DURING AXILLARY BRACHIAL-PLEXUS ANESTHESIA
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DOI：
10.1007/bf03011310
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发表时间：
1993-02-01
期刊：
影响因子：
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通讯作者：
YOON, HJ
中科院分区：
文献类型：
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作者：
TETZLAFF, JE;WALSH, M;YOON, HJ
研究了甲哌卡因pH值调节对腋路臂丛神经麻醉期间止血带疼痛发生率的影响。将39例计划进行手部手术的患者随机分为两组，在此期间计划使用充气止血带超过60分钟。两组均采用腋路臂丛神经阻滞，阻滞液为1.4%甲哌卡因40 ml，肾上腺素1.20万。研究组给予4 ml碳酸氢钠（1 mEq . ml-1）（最终pH 731），对照组加入4 ml盐水（最终pH 5.6）。止血带疼痛的发生率是根据止血带充气持续时间超过60分钟的病例确定的。止血带疼痛定义为局部不良，与不充分的腋窝阻滞不同。对照组止血带疼痛发生率更高。作者得出结论，计划长期使用充气止血带的病例可能适用于甲哌卡因碱化腋路臂丛麻醉。
The effect of pH adjustment of mepivacaine on the incidence of tourniquet pain during axillary brachial plexus anaesthesia was studied Thirty-nine patients scheduled for hand surgery, during which use of pneumatic tourniquet for longer than 60 min was planned, were randomized into two groups. Both received axillary brachial plexus block with 40 ml, 1.4% mepivacaine, 1.200,000 epinephrine. The study group had 4 ml sodium bicarbonate (1 mEq . ml-1) added (final pH 731), and the control group had 4 ml saline added (final pH 5.6). The incidence of tourniquet pain was determined from cases for which tourniquet inflation lasted longer than 60 min. Tourniquet, pain was defined as poorly localized and distinct from an inadequate axillary block by a blinded observer. More tourniquet pain occurred in the control group. The authors conclude that alkalinization of mepivacaine for axillary brachial plexus anaesthesia may be indicated in cases where use of pneumatic tourniquet for long periods is planned.