DESIGN AND ANALYSIS OF MICROCOILS FOR NMR MICROSCOPY

DESIGN AND ANALYSIS OF MICROCOILS FOR NMR MICROSCOPY
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DOI:
10.1006/jmrb.1995.1112
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发表时间:
1995-08-01
期刊:
JOURNAL OF MAGNETIC RESONANCE SERIES B
影响因子:
--
通讯作者:
LAUTERBUR, PC
LAUTERBUR, PC
中科院分区:
其他
文献类型:
--
作者:
PECK, TL;MAGIN, RL;LAUTERBUR, PC

文献摘要

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在核磁共振显微镜实验中实现的信噪比与射频线圈的性能直接相关。线圈性能的准确测定需要线圈的电阻被很好地表征。当导体的直径减小到操作频率下的电趋肤深度(delta)的尺寸时,用于描述较大NMR线圈的传统高频电路模型是不够的。一个更广泛的模型的基础上的缩放参数,包括三角洲。该模型补充了其他现有的电路模型,这些模型表示样本损耗、接地环路和寄生损耗以及RF线圈中感应的信号。在4.7 T(200 MHz)的H-1 NMR显微光谱实验中使用一系列螺线管微线圈完成实验验证。本研究首次证明,使用直径小至50 μ m的微弹簧圈可实现可预测的性能增强。(C)出版社:Academic Press
The signal-to-noise ratio achieved in a nuclear magnetic-resonance microscopy experiment is directly related to the performance of the radiofrequency coil. An accurate determination of coil performance requires that the resistance of the coil be well characterized, Traditional high-frequency electric-circuit models used to describe larger NMR coils are inadequate when the diameter of the conductor is reduced to the dimensions of the electrical skin depth (delta) at the frequency of operation. A more extensive model based on a scaling parameter that includes delta is presented. This model complements other existing circuit models that represent sample losses, ground-loop and parasitic losses, and the signal induced in the RF coil. Experimental verification is accomplished using a series of solenoidal microcoils in H-1 NMR microspectroscopy experiments at 4.7 T (200 MHz). This study demonstrates for the first time that a predictable performance enhancement is achieved using microcoils as small as 50 mu m in diameter. (C) 1995 Academic Press, Inc.