A method for the analysis of perfluorinated compounds in environmental and drinking waters and the determination of their lowest concentration minimal reporting levels
A method for the analysis of perfluorinated compounds in environmental and drinking waters and the determination of their lowest concentration minimal reporting levels
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DOI：
10.1016/j.chroma.2014.04.001
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发表时间：
2014-06-06
影响因子：
4.1
通讯作者：
Ferrario, Joseph
中科院分区：
文献类型：
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作者：
Boone, J. Scott;Guan, Bing;Ferrario, Joseph
建立了环境和饮用沃茨中17种全氟化合物（PFCs）的痕量分析方法。我们的目标是优化同位素稀释方法，以提高全氟化学品分析的精密度和准确度，并消除对基质匹配标准的需要。将250 mL环境水或饮用水样品缓冲至pH 4，加标标记的替代标准品，通过固相萃取柱进行萃取，并用氢氧化铵的甲基叔丁基醚：甲醇溶液进行洗脱。将样品洗脱液浓缩至体积，并通过液相色谱/串联质谱法（LC-MS/MS）进行分析。计算了17种全氟化学品的最低浓度最低报告水平（LCMRL），地表水为0.034 - 0.600纳克/升，饮用水为0.033 - 0.640纳克/升。所有化合物的相对标准偏差（RSD）为
A trace analytical method was developed for the determination of seventeen specific perfluorinated chemicals (PFCs) in environmental and drinking waters. The objectives were to optimize an isotope-dilution method to increase the precision and accuracy of the analysis of the PFCs and to eliminate the need for matrix-matched standards. A 250 mL sample of environmental or drinking water was buffered to a pH of 4, spiked with labeled surrogate standards, extracted through solid phase extraction cartridges, and eluted with ammonium hydroxide in methyl tert-butyl ether: methanol solution. The sample eluents were concentrated to volume and analyzed by liquid chromatography/tandem mass spectrometry (LC-MS/MS). The lowest concentration minimal reporting levels (LCMRLs) for the seventeen PFCs were calculated and ranged from 0.034 to 0.600 ng/L for surface water and from 0.033 to 0.640 ng/L for drinking water. The relative standard deviations (RSDs) for all compounds were