HIGHLY REITERATED SEQUENCES OF SIMIANSIMIANSIMIANSIMIANSIMIAN
HIGHLY REITERATED SEQUENCES OF SIMIANSIMIANSIMIANSIMIANSIMIAN
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DOI：
10.1126/science.205944
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发表时间：
1978-01-01
期刊：
影响因子：
56.9
通讯作者：
ROSENBERG, M
中科院分区：
文献类型：
--
作者：
ROSENBERG, H;SINGER, M;ROSENBERG, M
非洲绿色猴[Cercopithecus aethiops]基因组中重复数百万次的172个碱基对的DNA片段被鉴定。这个复杂单元的许多重复序列并不完全相同，而是代表一组密切相关的片段：序列分歧以非随机的方式发生在片段的不同位置。将从猴DNA获得的未克隆片段与在允许感染期间重组到猿猴病毒40基因组中的相同DNA的克隆片段进行比较。
A 172-base pair segment of DNA that is repeated several million times in the genome of the African green monkey [Cercopithecus aethiops] was characterized. The many repeats of this complex unit are not all identical but represent a set of closely related segments: sequence divergence occurs at various positions in the segment in a nonrandom manner. The uncloned segment obtained from monkey DNA is compared with a cloned segment of the same DNA which was recombined into the genome of simian virus 40 during permissive infection.