Efficacy of the Unified Protocol for transdiagnostic treatment of comorbid psychopathology accompanying emotional disorders compared to treatments targeting single disorders.
Efficacy of the Unified Protocol for transdiagnostic treatment of comorbid psychopathology accompanying emotional disorders compared to treatments targeting single disorders.
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DOI：
10.1016/j.jpsychires.2018.08.005
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发表时间：
2018-09
影响因子：
4.8
通讯作者：
Barlow DH
中科院分区：
文献类型：
--
作者：
Steele SJ;Farchione TJ;Cassiello-Robbins C;Ametaj A;Sbi S;Sauer-Zavala S;Barlow DH
这项研究的目的是检验统一方案(UP)，一种针对情绪障碍(即，焦虑、情绪和相关障碍)的跨诊断认知行为疗法，与已建立的针对特定障碍(例如，惊恐障碍)的单一障碍协议(SDP)相比，在治疗共发情绪障碍方面是否有效。参与者包括179名寻求门诊心理治疗的成年人。受试者年龄18~66岁，平均30.66岁(SD=10.77)。样本中55%是女性，主要是高加索人(83%)。诊断评估是通过焦虑障碍面谈时间表(ADIS)完成的，以及针对感兴趣的共病诊断的特定于障碍的、临床医生评级的措施。在两种治疗条件下，参与者的平均诊断次数从基线到治疗后显著下降，从基线到12个月的随访。此外，还观察到共病的广泛性焦虑(ESSG：UP=−1.72；SDP=−1.98)、社交焦虑(ESSG：UP=−1.33，−0.86；SDP=−1.60，−1.54)和抑郁(ESSG：UP=−0.83；SDP=−0.84)的变化。在组间比较中没有观察到显著差异。结果表明，UP和SDP都能有效地减轻共病情绪障碍的症状。讨论了跨诊断CBT的临床、实用和成本效益优势。
This study aimed to examine whether the Unified Protocol (UP), a transdiagnostic cognitive-behavioral therapy for emotional disorders (i.e., anxiety, mood, and related disorders), is efficacious in the treatment of co-occurring emotional disorders compared to established single disorder protocols (SDPs) that target specific disorders (e.g., panic disorder). Participants included 179 adults seeking outpatient psychotherapy. Participant age ranged from 18 to 66 years, with an average of 30.66 years (SD = 10.77). The sample was 55% female and mostly Caucasian (83%). Diagnostic assessments were completed with the Anxiety Disorder Interview Schedule (ADIS), and disorder-specific, clinician-rated measures for the comorbid diagnoses of interest. In both treatment conditions, participants’ mean number of diagnoses dropped significantly from baseline to posttreatment, and baseline to 12-month followup. Additionally, large effects were observed for changes in comorbid generalized anxiety (ESSG: UP = −1.72; SDP = −1.98), social anxiety (ESSG: UP = −1.33, −0.86; SDP = −1.60, −1.54), and depression (ESSG: UP = −0.83; SDP = −0.84). Significant differences were not observed in between-group comparisons. Results suggest that both the UP and SDPs are efficacious in reducing symptoms of comorbid emotional disorders. The clinical, practical, and cost-effective advantages of transdiagnostic CBT are discussed.
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6.9
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