Frequency of respiratory syncytial virus in hospitalized infants with lower acute respiratory tract infection in Colombia
Frequency of respiratory syncytial virus in hospitalized infants with lower acute respiratory tract infection in Colombia
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DOI：
10.1097/00006454-199612000-00014
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发表时间：
1996-12-01
影响因子：
3.6
通讯作者：
Trujillo, H
中科院分区：
文献类型：
--
作者：
Bedoya, VI;Abad, V;Trujillo, H
材料和方法。患者选择。本研究纳入了1994年4月至1995年4月在哥伦比亚麦德林总医院因下急性呼吸道感染住院的所有1岁以下患者。这些病人来自安蒂奥基亚州南部的不同城市和农村医疗中心。入院时记录的临床数据包括年龄、性别、入院前疾病持续时间、存在发热、咳嗽、呼吸急促（> 50次呼吸/min）、使用呼吸辅助肌、室内空气中发绀、呼气延长和呼气性喘鸣。收集的其他数据包括住院时间和抗生素治疗的存在和持续时间。入院后1小时内进行红细胞沉降率、白色血细胞计数、C反应蛋白和胸片检查，如果出现以下结果，则考虑病毒感染的诊断：白带增多、呼气延长、呼气性喘鸣、间质浸润、呼吸道感染和呼吸道感染。以及胸部X光片上的过度充气，以及三种或四种急性期反应物的阴性测试（< 20 000个白细胞/mm 3，< 10 000个多形核白细胞/mm 3，红细胞沉降率< 30 mm/h和C-反应蛋白< 7 mg/dl）。5，7-9如果有两个或更多的阳性急性期反应物，抗生素治疗开始，直到RSV免疫荧光的结果是可用的。
Materials and methods. Patient selection. All patients younger than 1 year old, who had been hospitalized for lower acute respiratory infection at the General Hospital of Medellín, Colombia, from April, 1994, to April, 1995, were enrolled in the study. These patients were sent from different urban and rural medical centers from the south of the State of Antioquia. Clinical data recorded on admission included age, sex, duration of the illness before admission, presence of fever, cough, tachypnea (> 50 respirations/min), use of respiratory accessory muscles, cyanosis in room air, prolonged expiration and expiratory wheezing. Other data collected were the duration of hospitalization and the presence and duration of antibiotic treatment. Erythrocyte sedimentation rate, white blood cell counts, C-reactive protein and chest radiographs were obtained during the first hours after admission.Diagnosis of viral infection was considered if the following findings were present: rhinorrhea; prolonged expiration; expiratory wheezing; interstitial infiltrates; and hyperinflation on chest radiographs, as well as negative tests for three or four acute phase reactants (< 20 000 leukocytes/mm 3,< 10 000 polymorphonuclear leukocytes/mm 3, erythrocyte sedimentation rate< 30 mm/h and C-reactive protein< 7 mg/dl). 5, 7-9 If there were two or more positive acute phase reactants, antibiotic therapy was begun until the result of RSV immunofluorescence was available.