Photon Detection: Current Status
Photon Detection: Current Status
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光子探测：当前状态
DOI：
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发表时间：
2017
期刊：
影响因子：
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通讯作者：
Masanobu Yamamoto
中科院分区：
文献类型：
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作者：
Masanobu Yamamoto
低光强荧光分析在流式细胞术和细胞生物学中具有重要意义。光电倍增管（PMT）由于其高灵敏度，多年来一直被用作光子检测设备;它可以通过真空中的倍增电极级联将单个光电子放大为数百万个电子。另外，光电倍增管中的光电阴极通过模拟光电流检测，具有检测面积大、动态范围宽的优点。近年来，基于微机电系统（MEMS）的光电倍增管和许多固态传感器，如硅光电二极管（PD），雪崩光电二极管（APD）和硅光电倍增管（SiPM）已被开发和改进，在UV到近IR波长。本章介绍了光电传感器的进展，特别是光子探测和潜在的应用。
Fluorescence analysis at low-level light intensity is important and inevitable for flow cytometry and cell biology. The photomultiplier (PMT) has been used as a photon-detection device for many years because of its high sensitivity; it can amplify a single photoelectron to millions of electrons by a cascade of dynodes in a vacuum. In addition, the photocathode in the PMT has the advantage of a wide detection area and wide dynamic range through analog photocurrent detection. Recently, microelectromechanical system (MEMS)-based PMTs and many solid-state sensors such as Si photodiodes (PDs), avalanche photodiodes (APDs), and Si photomultipliers (SiPMs) have been developed and improved in UV to near-IR wavelengths. Advancements in photosensors especially for photon detection and potential applications are described in this chapter.