SARS-CoV-2 is not present in the vaginal fluid of pregnant women with COVID-19
SARS-CoV-2 is not present in the vaginal fluid of pregnant women with COVID-19
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DOI：
10.1080/14767058.2020.1793318
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发表时间：
2020-07-14
影响因子：
1.8
通讯作者：
Ozden, Selcuk
中科院分区：
文献类型：
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作者：
Aslan, Mehmet Musa;Uslu Yuvaci, Hilal;Ozden, Selcuk
背景关于SARS-CoV-2在女性生殖系统中的存在的数据很少；然而，这一信息对于了解该病毒是否可以通过性传播或从母婴传播是重要的。本研究的目的是调查新冠肺炎携带者孕妇是否存在下生殖道病毒。方法在这项横断面研究中，我们对2020年4月19日至5月19日在一所三级大学医院收集的前瞻性数据进行了分析。我们包括13名疑似新冠肺炎患者住院治疗的孕妇。对临床诊断为新冠肺炎的孕妇的实验室检测、影像检测和阴道拭子核酸检测结果进行了分析。结果12例确诊为新冠肺炎的孕妇进入本研究。平均年龄为32+/-7.9岁。所有患者都有轻微的症状，并在产科病房进行了随访，没有人需要重症监护病房的随访。所有下生殖道样本均为SARS-CoV-2阴性。结论孕妇阴道液中未检出SARS-CoV-2。这一发现可能表明女性生殖道不是SARS-CoV-2的传播途径。
Background Data concerning the presence of SARS-CoV-2 in the female genital system is scarce; however, this information is important for understanding whether the virus can transmit sexually or from mother to child. The aim of this study was to investigate whether pregnant women with COVID-19 have virus in their lower genital tract. Methods In this cross-sectional study, we present an analysis of prospectively gathered data collected at a single tertiary university hospital from 19 April to 19 May 2020. We included 13 pregnant women hospitalized with suspected COVID-19. Results of laboratory tests, imaging tests, and nucleic acid tests on vaginal swabs for SARS-CoV-2 were also analyzed for pregnant women with a clinical diagnosis of COVID-19. Results Twelve pregnant women with confirmed COVID-19 were included in this study. Mean age was 32 +/- 7.9 years. All patients had mild symptoms and were followed in the maternity ward, with none of them needing critical care unit follow-up. All lower genital tract samples were negative for SARS-CoV-2. Conclusion We demonstrated that SARS-CoV-2 was not present in the vaginal fluid of pregnant women. This finding may indicate that the female genital tract is not a route of SARS-CoV-2 transmission.