The complex ecology of hantavirus in Paraguay
The complex ecology of hantavirus in Paraguay
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DOI：
10.4269/ajtmh.2003.69.263
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发表时间：
2003-09-01
影响因子：
3.3
通讯作者：
Jonsson, CB
中科院分区：
文献类型：
--
作者：
Chu, YK;Owen, RD;Jonsson, CB
1995年巴拉圭查科暴发汉坦病毒肺综合征(HPS)后，劳氏华支睾吸虫被确定为与这些病例相关的汉坦病毒的啮齿宿主。为了探索在巴拉圭感染更多汉坦病毒的可能性，我们从17个部门中的10个部门收集了636只哺乳动物。阿尔托、巴拉圭、查科和东部涅姆布库、伊塔普亚的27只动物的血浆对安第斯病毒抗原有抗体。在这27个人中，有5个人(在4个物种中)汉坦病毒RNA阳性。收集了巴拉圭东部土著居民的血清，以确定是否有人在查科以外的地方感染了汉坦病毒。17%的人抗体呈阳性。这些结果表明，几种不同的汉坦病毒在巴拉圭共同传播，巴拉圭东部发生的HPS病例可能是由于接触了与查科不同的汉坦病毒造成的。
Following an outbreak of hantavirus pulmonary syndrome (HPS) in the Paraguayan Chaco in 1995, Calomys laucha was identified as the rodent host for the hantavirus associated with these cases. To explore the possibility of additional hantaviruses in Paraguay, we collected 636 mammals from 10 of the 17 departments. Plasma from 27 animals in Alto Paraguay and Boqueron in the Chaco and Neembucu and Itapua in the eastern region had antibody to Andes virus antigens. Of these 27, five individuals (among four species) were positive for hantavirus RNA. Sera were collected from indigenous people in eastern Paraguay to ascertain whether persons were being infected with hantavirus outside of the Chaco. Seventeen percent were antibody-positive. These results suggest that several different hantaviruses are co-circulating in Paraguay, and that HPS cases occurring in eastern Paraguay may result from exposure to hantaviruses that are distinct from those in the Chaco.