GPCRDB:: an information system for G protein-coupled receptors
GPCRDB:: an information system for G protein-coupled receptors
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DOI：
10.1093/nar/26.1.275
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发表时间：
1998-01-01
影响因子：
14.9
通讯作者：
Vriend, G
中科院分区：
文献类型：
--
作者：
Horn, F;Weare, J;Vriend, G
GPCRDB是一个G蛋白偶联受体（GPCR）数据库系统，旨在收集和传播GPCR相关数据，它保存序列、突变体数据和配体结合常数作为主要（实验）数据。添加了多序列比对、三维模型、系统发育树和二维可视化工具等计算衍生数据，以增强数据库的实用性。GPCRDB 是欧盟资助的项目，旨在构建能够处理高度异构数据的通用分子类特定数据库。选择 GPCR 作为测试分子是因为它们对医学科学具有巨大的重要性，并且可以获取大量高度异构的数据。 GPCRDB 可通过 WWW 获取：http://www.gpcr.org/7tm。
The GPCRDB is a G protein-coupled receptor (GPCR) database system aimed at the collection and dissemination of GPCR related data, It holds sequences, mutant data and ligand binding constants as primary (experimental) data. Computationally derived data such as multiple sequence alignments, three dimensional models, phylogenetic trees and two dimensional visualization tools are added to enhance the database's usefulness, The GPCRDB is an EU sponsored project aimed at building a generic molecular class specific database capable of dealing with highly heterogeneous data. GPCRs were chosen as test molecules because of their enormous importance for medical sciences and due to the availability of so much highly heterogeneous data. The GPCRDB is available via the WWW at http://www.gpcr.org/7tm.