RESPONSE TO STATIC TILTS OF PERIPHERAL NEURONS INNERVATING OTOLITH ORGANS OF SQUIRREL-MONKEY
RESPONSE TO STATIC TILTS OF PERIPHERAL NEURONS INNERVATING OTOLITH ORGANS OF SQUIRREL-MONKEY
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DOI：
10.1152/jn.1972.35.6.978
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发表时间：
1972-01-01
影响因子：
2.5
通讯作者：
ABEND, WK
中科院分区：
文献类型：
--
作者：
FERNANDEZ, C;GOLDBERG, JM;ABEND, WK
前庭（18，27，28，34，35）和侧线器官（7，16）的毛细胞具有由动纤毛和静纤毛的相对位置决定的形态极化。在这种极化和相关的传入神经纤维的生理学之间存在明确的关系。这一结论首先由洛温斯坦和韦索尔（ZZ）得出，他们指出，对于半规管，使毛向动纤毛弯曲的刺激导致放电增加，相反方向的刺激导致放电减少。半规管的情况很简单。对于支配给定神经管（14，21）的所有传入神经，功能极化是相同的，并且与此相关，所有毛细胞具有相同的取向。耳石器官呈现出更为复杂的图景。在椭圆囊和小囊中，毛细胞的取向有系统的变化。因此，可以预期，耳石神经元的功能极化在不同的耳石神经元之间是不同的。这也许就是生理学文献被混淆的原因。举一个混淆的例子，两个关于椭圆囊传入神经反应的最完整的研究--洛温斯坦和罗伯茨（20）对棘背鳐的研究和贝伦斯（2）对猫的研究--在同侧耳向下倾斜是否会导致放电的增加或减少方面存在分歧。不可否认，这两项研究使用了完全不同的物种。矛盾之处在于，决不在于此。s，令人不安，特别是因为形态极性-
THE HAIR CELLS of the vestibular(18, 27, 28, 34, 35) and of the lateral-line organs (7, 16) possess a morphological polarization determined by the relative positions of the kinocilium and stereocilia. There is a definite relation between this polarization and the physiology of the associated afferent nerve fibers. This conclusion was first arrived at by Lowenstein and Wersall(ZZ), who pointed out that, for the semicircular canals, stimuli which bend the hairs toward the kinocilium result in an increase in discharge, oppositely directed stimuli a decrease in discharge. The situation in the semicircular canals is simple. The functional polarization is identical for all afferents innervating a given canal (14, 21) and, correlated with this, all of the hair cells have the same orientation. The otolith organs present a more complicated picture. In both the utriculus and sacculus, there is a systematic variation in the orientation of the hair cells. It might be expected then that the functional polarization would differ from one otolith neuron to another. This is perhaps the reason why the physiological literature is confused. To cite one example of the confusion, the two most complete studies of the response of utricular afferents-that of Lowenstein and Roberts(20) in the thornback ray and that of Beerens (2) in the cat-disagree as to whether a downward tilt of the ipsilateral ear results in an increase or a decrease in firing. Admittedly, quite different species were used in the two studies. The discrepancy is, never thele.; s, disturbing, particularly since the morphological polar-