Enantioselective addition of aryllithium reagents to aromatic imines mediated by 1,2-diamine ligands
Enantioselective addition of aryllithium reagents to aromatic imines mediated by 1,2-diamine ligands
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DOI：
10.1016/j.tetlet.2004.04.100
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发表时间：
2004-06-07
影响因子：
1.8
通讯作者：
Alexakis, A
中科院分区：
文献类型：
--
作者：
Cabello, N;Kizirian, JC;Alexakis, A
以N，N ′-四甲基环己烷-1，2-二胺为手性配体，通过芳基锂试剂与芳香亚胺的加成反应，合成了一系列光学富集胺。可获得高达90%的对映体过量。(C)2004爱思唯尔有限公司保留所有权利。
A variety of optically enriched amines have been obtained by addition of aryllithium reagents to aromatic imines using N,N'-tetramethylcyclohexane-1,2-diamine as chiral ligands. Enantiomeric excesses up to 90% could be obtained. (C) 2004 Elsevier Ltd. All rights reserved.