IS GAIT SPEED A VALID MEASURE TO PREDICT COMMUNITY AMBULATION IN PATIENTS WITH PARKINSON'S DISEASE?
IS GAIT SPEED A VALID MEASURE TO PREDICT COMMUNITY AMBULATION IN PATIENTS WITH PARKINSON'S DISEASE?
复制标题
DOI：
10.2340/16501977-1123
复制
发表时间：
2013-04-01
影响因子：
3.5
通讯作者：
Kwakkel, Gert
中科院分区：
文献类型：
--
作者：
Elbers, Roy G.;van Wegen, Erwin E. H.;Kwakkel, Gert
目的：为了探讨帕金森病社区步行步态速度的预测价值，并建立一个多变量预测模型为社区walking.Design：从基线评估的数据在一个随机临床试验中被used.Subjects：共153例帕金森病患者included.Methods：社区步行进行了评估使用的诺丁汉扩展活动的日常生活指数（NEAI）的流动性域。在项目1（“你在外面走动吗？“）和第5项（“你有没有过马路？“）被认为是社区步行者。用6米或10米计时步行试验测量步态速度。年龄、性别、婚姻状况、病程、疾病严重程度、运动障碍、平衡、步态僵硬、害怕跌倒、既往福尔斯史、认知功能、执行功能、疲劳、焦虑和抑郁对多变量模型的贡献进行了调查。0.88 m/s的步态速度正确预测了70%的患者为社区步行者。多变量模型，包括步态速度和害怕跌倒，正确预测78%的患者作为社区walkers.Conclusion：定时步行测试是有效的测量，以预测帕金森病社区步行。然而，对社区步行的评估应包括对跌倒恐惧的评估。
Objective: To investigate the predictive value of gait speed for community walking in Parkinson's disease and to develop a multivariate prediction model for community walking.Design: Data from baseline assessments in a randomized clinical trial were used.Subjects: A total of 153 patients with Parkinson's disease were included.Methods: Community walking was evaluated using the mobility domain of the Nottingham Extended Activities of Daily Living Index (NEAI). Patients who scored 3 points on item 1 ("Did you walk around outside?") and item 5 ("Did you cross roads?") were considered community walkers. Gait speed was measured with the 6-m or 10-m timed walking test. Age, gender, marital status, disease duration, disease severity, motor impairment, balance, freezing of gait, fear of falling, previous falls, cognitive function, executive function, fatigue, anxiety and depression were investigated for their contribution to the multivariate model.Results: Seventy patients (46%) were classified as community walkers. A gait speed of 0.88 m/s correctly predicted 70% of patients as community walkers. The multivariate model, including gait speed and fear of falling, correctly predicted 78% of patients as community walkers.Conclusion: Timed walking tests are valid measurements to predict community walking in Parkinson's disease. However, evaluation of community walking should include an assessment of fear of falling.