Single-gene greenbeard effects in the social amoeba Dictyostelium discoideum
Single-gene greenbeard effects in the social amoeba Dictyostelium discoideum
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DOI：
10.1126/science.1077742
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发表时间：
2003-01-03
期刊：
影响因子：
56.9
通讯作者：
Strassmann, JE
中科院分区：
文献类型：
--
作者：
Queller, DC;Ponte, E;Strassmann, JE
如果利他等位基因通过帮助亲属来帮助自己的拷贝，那么选择就会有利于生殖利他主义。另一种“绿胡子”机制，即等位基因直接识别并帮助其他等位基因复制自身，通常被认为过于复杂，单个基因无法完成。盘状盘齿龙的csA基因作为单基因绿须。当野生型细胞与csa敲除细胞混合时，野生型细胞更加利他，但也能够优先将利益导向其他野生型细胞。这两种特性都直接来自于csA编码的蛋白的亲同性细胞粘附。
Selection can favor reproductive altruism if an altruism allele aids copies of itself by helping relatives. The alternative "greenbeard" mechanism, in which an allele directly recognizes and aids copies of itself in others, is generally thought to be too complex for a single gene to carry out. The csA gene in Dictyostelium discoideum acts as a single-gene greenbeard. When wild-type cells are mixed with csA-knockout cells, the wild type is more altruistic, but is also able preferentially to direct the benefits to other wild-type cells. Both properties derive directly from homophilic cell adhesion of the protein encoded by csA.