Voluntary breath-holding for breast cancer radiotherapy is consistent and stable
Voluntary breath-holding for breast cancer radiotherapy is consistent and stable
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DOI：
10.1259/bjr.20150309
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发表时间：
2015-01-01
影响因子：
2.6
通讯作者：
Donovan, Ellen M.
中科院分区：
文献类型：
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作者：
Colgan, Ruth;James, Matthew;Donovan, Ellen M.
目的：对自愿屏气(VBH)技术的屏气稳定性和稳定性进行回顾性分析。方法：对19例患者多次屏气的电子门脉图像数据进行电影循环序列分析，以评估屏气内和屏气之间的稳定性。对31例VBH患者和一组自由呼吸(FB)患者的基于电子射野成像(EPI)的体内剂量学数据进行了分析，以提供参考。体模实验模拟了FB剂量、屏气和计划外屏气释放的影响。结果：165/174(93%)电影循环数据集没有检测到位移。其余12例，中位移位=1.5 mm，最大移位=3 mm(1个部分1例)。体内剂量学数据分析显示，计划剂量的中位数差异为20.2%(VBH)和-0.1%(FB)。包括肺部区域在内的剂量分布评估(伽马)通过率分别为84%(VBH)和91%(FB)；肺部优先的情况下分别为93%和96%。计划外释放体模屏气姿势改变了中位数剂量
Objective: To evaluate breath-hold stability and constancy for a voluntary breath-hold (VBH) technique in a retrospective analysis.Methods: Movie loop sequences of electronic portal image data from multiple breath holds in a cohort of 19 patients were used to assess within and between breath-hold stability. In vivo dosimetry data based on electronic portal imaging (EPI) were analysed for 31 VBH patients plus a cohort of free-breathing (FB) patients to provide a reference. A phantom experiment simulated the impact on dose of FB, breath hold and unplanned release of breath hold.Results: 165/174 (93%) movie loop data sets had no detectable displacement. For the remaining 12, median displacement = 1.5 mm and maximum displacement = 3 mm (one patient on one fraction). In vivo dosimetry data analysis showed a median dose difference measured to planned of 20.2% (VBH) and -0.1% (FB). Dose distribution evaluation (gamma) pass rates were 84% (VBH) and 91% (FB) including the lung region; 93% and 96% with a lung override. Unplanned release of phantom breath-hold position changed median dose by