Urinary, faecal and sexual dysfunction in patients with multiple sclerosis
Urinary, faecal and sexual dysfunction in patients with multiple sclerosis
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DOI：
10.1007/s004150050508
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发表时间：
1999-11-01
影响因子：
6
通讯作者：
Compston, DAS
中科院分区：
文献类型：
--
作者：
Hennessey, A;Robertson, NP;Compston, DAS
在一项以人群为基础的研究中，221名多发性硬化症患者通过邮寄问卷调查了膀胱和肠道功能障碍的患病率和性质。这项初步调查还补充了个人审查，其中还提供了174名参与者的性功能障碍信息和152名参与者的实验室和尿动力学测试信息。221例患者中有30例（14%）目前使用留置导尿，其余190例中有84例（44%）报告有尿功能障碍症状，其中最常见的是尿急和尿频。144例患者中有13例（9%）存在肾功能不全的生化证据，132例患者中有40例（30%）存在尿样感染。在54例患者中，11例认为上尿路检查是适当的，结果显示异常。221例患者中64例（29%）出现大便失禁，120例（54%）出现便秘。68名男性中有56名（82%）和106名女性中有55名（52%）报告性活动恶化，最常见的症状是男性勃起功能障碍和女性疲劳。
The prevalence and nature of bladder and bowel dysfunction were examined in a population-based study of 221 patients with multiple sclerosis who returned postal questionnaires. This preliminary investigation was supplemented by personal review which also provided information on sexual dysfunction in 174 and laboratory and urodynamic tests in 152 participants. Thirty of 221 (14%) currently used an indwelling catheter, and 84 of the remainding 190 (44%) reported symptoms of urinary dysfunction, of which the most common were urgency and frequency. Thirteen of 144 (9%) patients had biochemical evidence of renal dysfunction, and 40 of 132 (30%) had infected urine samples. Eleven of 54 patients in whom investigation of upper urinary tract was thought to be appropriate demonstrated abnormalities. Sixty-four of 221 (29%) patients had experienced faecal incontinence, and 120 of 221 (54%) were constipated. Fifty-six of 68 (82%) men and 55 of 106 (52%) women reported a deterioration in sexual activity, the commonest symptoms being erectile failure in men and fatigue in women.