Influence of virgin coconut oil-enriched diet on the transcriptional regulation of fatty acid synthesis and oxidation in rats - a comparative study
Influence of virgin coconut oil-enriched diet on the transcriptional regulation of fatty acid synthesis and oxidation in rats - a comparative study
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DOI：
10.1017/s000711451400004x
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发表时间：
2014-05-28
影响因子：
3.6
通讯作者：
Rajamohan, Thankappan
中科院分区：
文献类型：
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作者：
Arunima, Sakunthala;Rajamohan, Thankappan
本研究比较了椰子油(VCO)与椰子油、橄榄油、葵花籽油对正常大鼠体内脂肪酸合成、氧化及脂肪酸代谢的分子调控作用。雄性SpragueDawley大鼠在饲喂合成饲料的同时，以8%的比例饲喂试验油45d。日粮中添加VCO可降低组织脂质水平，降低脂肪生成相关酶即酰辅酶A羧基酶和脂肪酸合成酶(Fas)的活性(P
The present study was carried out to evaluate the effects of virgin coconut oil (VCO) compared with copra oil, olive oil and sunflower-seed oil on the synthesis and oxidation of fatty acids and the molecular regulation of fatty acid metabolism in normal rats. Male Sprague-Dawley rats were fed the test oils at 8% for 45 d along with a synthetic diet. Dietary supplementation of VCO decreased tissue lipid levels and reduced the activity of the enzymes involved in lipogenesis, namely acyl CoA carboxylase and fatty acid synthase (FAS) (P