Empirical Scaling of the Stages of Cognitive Decline in Senile Dementia

Empirical Scaling of the Stages of Cognitive Decline in Senile Dementia
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老年痴呆症认知衰退阶段的实证衡量

DOI:
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发表时间:
1990
影响因子:
2.6
通讯作者:
J. Lesser
J. Lesser
中科院分区:
医学4区
文献类型:
--
作者:
J. Overall;J. Scott;H. Rhoades;J. Lesser

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在我院老年门诊就诊的115名老年患者中,由一名亲属或护理人员填写了一份30项有关认知能力下降体征和症状的问卷。计算了12种不同的初步量表值,以确定30种临床表现中每一种的严重程度。然后使用主成分分析将12个初步指标组合成一个更可靠地代表30个临床表现之间距离的单一复合量表。临床表现的量表得分被观察到聚集成相对离散的组,表明自然发生的阶段或阶段。目的聚类分析方法进一步表明,在认知衰退连续体中存在不同的新损伤发生阈值。建议在原发性退行性痴呆病程分期中使用经验推导的量表值。[J]中华老年精神病学杂志1990;3:212-220。
A 30-item questionnaire concerned with signs and symptoms of cognitive decline was completed by a relative or caregiver for each of 115 elderly patients seen in the gerontology outpatient clinic of our institution. Twelve different preliminary scale values were calculated to locate each of the 30 clinical manifestations along a continuum of increasing severity. Prin cipal components analysis was then used to combine the 12 preliminary indices into a single composite scale that more reliably represents distances between the 30 clinical manifestations. The scale scores for the clinical manifestations were observed to cluster into relatively discrete groups, suggesting naturally occurring stages or phases. Objective cluster anal ysis methods further suggested the presence of distinct thresholds for occurrence of new impairments along the cognitive decline continuum. Utility of the empirically derived scale values in staging the course of primary degenerative dementia is suggested. (J Geriatr Psychiatry Neurol 1990;3:212-220).
阿尔茨海默氏型痴呆的有序功能评估工具。
DOI: 10.1176/ps.36.6.593
发表时间: 1985
期刊: Hospital & community psychiatry
影响因子: --
作者:
Reisberg,B;Ferris,SH;Franssen,E
通讯作者: Franssen,E