Mutagen Formation Potential (MFP) of Kotsuki River Water and Contribution of Pesticides to MFP
Mutagen Formation Potential (MFP) of Kotsuki River Water and Contribution of Pesticides to MFP
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DOI：
10.2965/jwet.2011.349
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发表时间：
2011
影响因子：
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通讯作者：
K. Abiru;H. Takanashi;M. Kishida;T. Nakajima;A. Ohki
中科院分区：
文献类型：
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作者：
K. Abiru;H. Takanashi;M. Kishida;T. Nakajima;A. Ohki
研究了所选农药对河水诱变剂形成潜力（MFP）的贡献。通过四极杆 GC-MS 测定河水样品中农药的浓度。在小月川采集的水样中检测到了 39 种农药中的 12 种。使用未通过 S9 mix (TA100-S9) 进行代谢激活的鼠伤寒沙门氏菌 TA100 进行 Ames 致突变性测定（预孵育法）来测量 MFP。从收集的所有样本中，检测到了显着的 MFP。农药对河水样品MFP的最大贡献为0.11%，表明本研究发现的农药对河水样品MFP的影响不显着。应调查农药降解产物对河水MFP的贡献，了解农药降解产物是否影响河水MFP。
The contribution of selected pesticides to the mutagen formation potential (MFP) of river waters was studied. The concentrations of the pesticides in river water samples were determined by means of a quadrupole GC-MS. Twelve out of 39 pesticides measured were detected in the water samples collected from Kotsuki River. Ames mutagenicity assays (preincubation method) using Salmonella typhimurium TA100 without metabolic activation by S9 mix (TA100-S9) were performed to measure the MFP. From all the samples collected, significant MFPs were detected. The maximum contribution of the pesticides to the MFP of the river water samples was 0.11%, indicating that the effect of the pesticides found in this study on the MFP of the river water samples is insignificant. The contribution of pesticide degradation products to the MFP of river waters should be investigated in order to see whether pesticide degradation products affect the MFP of river waters.