Current status of cortisol findings in post-traumatic stress disorder

Current status of cortisol findings in post-traumatic stress disorder
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DOI:
10.1016/s0193-953x(02)00002-3
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发表时间:
2002-06-01
影响因子:
1.7
通讯作者:
Yehuda, R
Yehuda, R
中科院分区:
医学3区
文献类型:
--
作者:
Yehuda, R

文献摘要

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本文总结了创伤后应激障碍(PTSD)中下丘脑-垂体-肾上腺轴改变的发现,并评估了在已发表的研究中缺乏一致性的可能原因。由方法学和解释性差异引起的差异来源被强调,但不同的发现被解释为说明了一个比以前描述的更复杂的PTSD神经内分泌学。
This article summarizes findings of hypothalamic-pituitary-adrenal axis alterations in post-traumatic stress disorder (PTSD) and evaluates likely reasons for the lack of agreement among published studies. sources of variance caused by methodologic and interpretative differences are highlighted, but the disparate findings are explained as illustrating a more complex neuroendocrinology of PTSD than has previously been described.