The place of the hippocampus in fear conditioning
The place of the hippocampus in fear conditioning
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DOI：
10.1016/s0014-2999(03)01283-4
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发表时间：
2003-02-28
影响因子：
5
通讯作者：
Fanselow, MS
中科院分区：
文献类型：
--
作者：
Sanders, MJ;Wiltgen, BJ;Fanselow, MS
巴甫洛夫恐惧条件反射是一种适合于实验室分析恐惧神经生物学和学习记忆神经机制研究的现象。研究人员在描述恐惧条件反射的神经回路和神经化学方面取得了很大进展。海马体在背景恐惧中的位置仍然是一个有争议的问题。在这篇综述中，我们研究海马在恐惧条件反射中起作用的证据。然后，我们批判性地研究其在学习和记忆的线索和上下文恐惧条件反射的确切作用的假设。(C)2003 Elsevier Science B.V.保留所有权利。
Pavlovian fear conditioning is a phenomenon amenable to laboratory analysis of the neurobiology of fear and the investigation of neural mechanisms of learning and memory. Investigators have made much progress in delineating the neurocircuitry and neurochemistry of fear conditioning. The place of the hippocampus in context fear remains a controversial issue. In this review, we examine the evidence that the hippocampus plays a role in fear conditioning. We then critically examine hypotheses concerning its exact role in learning and memory for cued and context fear conditioning. (C) 2003 Elsevier Science B.V. All rights reserved.