Prevalence and age of onset for drug use in seven international sites: results from the international consortium of psychiatric epidemiology
Prevalence and age of onset for drug use in seven international sites: results from the international consortium of psychiatric epidemiology
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DOI：
10.1016/s0376-8716(02)00224-7
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发表时间：
2002-12-01
影响因子：
4.2
通讯作者：
Wittchen, HU
中科院分区：
文献类型：
--
作者：
Vega, WA;Aguilar-Gaxiola, S;Wittchen, HU
本研究比较了六个国际站点中酒精、大麻和其他药物的终生患病率和首次使用（发病）年龄。国际精神病学流行病学联合会（ICPE）收集了来自七个流行病学现场调查的数据，这些调查使用了兼容的仪器和研究设计。使用世界卫生组织的综合国际诊断仪器（卫生组织-国际诊断仪器）和其他项目来确定每个地点的药物使用情况。估计了酒精、大麻和其他非法药物的终生使用率。生存分析用于估计发病年龄。研究环境和主要结果：饮酒12次或12次以上依次为：荷兰（86.3%）、美国（71.7%）、加拿大安大略省（71.6%）；巴西圣保罗（66.1%）、德国慕尼黑（64.9%）、美国加州弗雷斯诺（51.9%）、墨西哥城（43.2%）。一生中使用大麻五次或五次以上的比例从美国的28.8%到墨西哥城的1.7%不等，其他药物的比例从美国（19.4%）到墨西哥城（1.7%）不等。不同研究地点的首次使用年龄相似。该研究表明，不同年龄的发病模式基本一致，而不同地点的终生患病率差异很大。研究结果表明，来自低消费国家的移民人口的药物使用模式可能会因在比率较高的国家进行国际重新安置而发生变化。本文还讨论了本研究方法上的局限性以及对未来国际比较研究的建议。(C) 2002爱思唯尔科学爱尔兰有限公司版权所有。
This study compares lifetime prevalence and age of first use (onset) for alcohol, cannabis, and other drugs in six international sites. Data from seven epidemiologic field surveys that used compatible instruments and study designs were compiled for cross-site analyses by the International Consortium of Psychiatric Epidemiology (ICPE). The world health organization's composite international diagnostic instrument (WHO-CIDI) and additional items were used to ascertain drug use in each site. Lifetime use rates were estimated for alcohol, cannabis, and other illicit drugs. Survival analyses were used to estimate age of onset. Study settings and main results: use of alcohol twelve or more times ranged in descending order from the Netherlands (86.3%), United States (71.7%), Ontario, Canada (71.6%); Sao Paulo, Brazil (66.1%), Munich, Germany (64.9%), Fresno, California (USA) (51.9%), to Mexico City (43.2%). Use of cannabis five or more times in a lifetime ranged from 28.8 in the United States to 1.7% in Mexico City, and other drugs ranged from United States (19.4%) to Mexico City (1.7%). Age of first use was similar across study sites. This study demonstrates the fundamental uniformity of onset patterns by age as contrasted with wide variations in lifetime prevalences across sites. Study findings suggest that drug use patterns may change among emigrating populations from low consumption nations as a consequence of international resettlement in nations with higher rates. Methodological limitations of the study along with recommendations for future international comparative research are discussed. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.