A molecular phylogeny of the hominoid primates as indicated by two-dimensional protein electrophoresis.
A molecular phylogeny of the hominoid primates as indicated by two-dimensional protein electrophoresis.
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二维蛋白质电泳显示的人科灵长类动物的分子系统发育。
DOI：
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发表时间：
1987
影响因子：
11.1
通讯作者：
S. O’Brien
中科院分区：
文献类型：
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作者：
D. Goldman;P. Giri;S. O’Brien
利用双向电泳（2DE）分析的383条放射性标记的成纤维细胞多肽的遗传距离，构建了类人猿灵长类的分子遗传学模型。一个内部一致的矩阵的Nei遗传距离的基础上产生的变体在电泳位置。衍生的系统发育树表明一个分支序列，从最古老的到最近的，猕猴（食蟹猴），gibbon-siamang，猩猩，大猩猩，和人类黑猩猩。240电泳性状的分支分析，不同猿种之间产生了相同的树。通过2DE获得的遗传距离的措施是在很大程度上与其他分子程序产生的一致。此外，2DE数据集似乎解决了人类-黑猩猩-大猩猩的脊髓切断术，有利于黑猩猩和人类的更近的关联。
A molecular phylogeny for the hominoid primates was constructed by using genetic distances from a survey of 383 radiolabeled fibroblast polypeptides resolved by two-dimensional electrophoresis (2DE). An internally consistent matrix of Nei genetic distances was generated on the basis of variants in electrophoretic position. The derived phylogenetic tree indicated a branching sequence, from oldest to most recent, of cercopithecoids (Macaca fascicularis), gibbon-siamang, orangutan, gorilla, and human-chimpanzee. A cladistic analysis of 240 electrophoretic characters that varied between ape species produced an identical tree. Genetic distance measures obtained by 2DE are largely consistent with those generated by other molecular procedures. In addition, the 2DE data set appears to resolve the human-chimpanzee-gorilla trichotomy in favor of a more recent association of chimpanzees and humans.