Incidence and Epidemiology of Cervical Radiculopathy in the United States Military 2000 to 2009

Incidence and Epidemiology of Cervical Radiculopathy in the United States Military 2000 to 2009
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DOI:
10.1097/bsd.0b013e31820d77ea
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发表时间:
2012-02-01
影响因子:
--
通讯作者:
Caram, Pedro M., Jr.
Caram, Pedro M., Jr.
中科院分区:
医学3区
文献类型:
--
作者:
Schoenfeld, Andrew J.;George, Alan A.;Caram, Pedro M., Jr.

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研究设计:流行病学回顾前瞻性收集的军事数据库。目的:这项调查旨在确定2000年至2009年美国军队人群中颈神经根病的发病率及其发展的风险因素。背景资料摘要:目前,颈神经根病的流行病学仍然知之甚少,其发展的风险因素尚未得到可靠的定义。方法:军方的国防医学流行病学数据库用于识别2000年至2009年期间诊断为颈神经根病(国际疾病分类代码723.4)的所有军人。获得了所有识别个体的人口统计学数据,包括年龄组、性别、种族、军衔和服务的分支。在所研究的时间段内,武装部队内的所有服役人员都记录了类似的数据。计算颈神经根病的发病率,并确定未校正的发病率比。风险因素进行了分析,通过执行多变量泊松回归分析,控制所有其他因素内model.Results:在2000年和2009年之间,约24,742人被诊断为颈椎神经根病的人群中的风险13,813,333,发病率为1.79每1000人年。每个连续年龄组校正后的发病率比值具有统计学显著性差异(P < 0.001),95%置信区间相互排斥。年龄在40岁及以上的人被发现有最大的风险颈椎神经根病。女性性(P < 0.001),白色人种(P < 0.001),职级结构内的高级职务(P < 0.001),在军队服役(P < 0.001)或空军(P = 0.01)也被认为是颈神经根病的重要危险因素。这项研究是第一次尝试定义颈神经根病的发病率,并描述其在美国人群中发展的危险因素。研究结果表明,年龄很可能是颈椎神经根病的最大危险因素,女性、白色种族、高级军事职位和陆军或空军服役也不同程度地影响风险。
Study Design: Epidemiological review of a prospectively collected military database.Objective: This investigation sought to determine the incidence of cervical radiculopathy and risk factors for its development within the population of the United States military from 2000 to 2009.Summary of Background Data: Currently, the epidemiology of cervical radiculopathy remains poorly understood and risk factors for its development have not been reliably defined.Methods: The military's Defense Medical Epidemiological Database was used to identify all servicemembers diagnosed with cervical radiculopathy (International Classification of Diseases code 723.4) between 2000 and 2009. Demographic data was obtained for all identified individuals including age group, sex, race, military rank, and branch of service. Like data was recorded for all servicemembers within the Armed Forces during the time period under study. The incidence of cervical radiculopathy was calculated and unadjusted incidence rate ratios were determined. Risk factors were analyzed by performing multivariate Poisson regression analysis, controlling for all other factors within the model.Results: Between 2000 and 2009, about 24,742 individuals were diagnosed with cervical radiculopathy among a population-at-risk of 13,813,333, for an incidence of 1.79 per 1000 person-years. Statistically significant differences (P < 0.001) in adjusted incidence rate ratios were identified for each successive age group with mutually exclusive 95% confidence intervals. Those age 40 years and above were found to have the greatest risk of cervical radiculopathy. Female sex (P < 0.001), White race (P < 0.001), senior positions within the rank structure (P < 0.001), and service in the Army (P < 0.001) or Air Force (P = 0.01) were also identified as significant risk factors for cervical radiculopathy.Conclusions: This study is the first to attempt to define the incidence of cervical radiculopathy and characterize risk factors for its development within an American population. Findings presented here indicate that age is most likely the greatest risk factor for cervical radiculopathy, with female sex, White race, senior military positions, and Army or Air Force service also influencing risk to varying degrees.