RESPONSES OF MIDBRAIN DORSAL RAPHE NEURONS TO ETHANOL STUDIED IN BRAIN-STEM SLICES
RESPONSES OF MIDBRAIN DORSAL RAPHE NEURONS TO ETHANOL STUDIED IN BRAIN-STEM SLICES
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DOI：
10.1016/0741-8329(87)90069-3
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发表时间：
1987-09-01
期刊：
影响因子：
2.3
通讯作者：
KEENAN, L
中科院分区：
文献类型：
--
作者：
CHU, NS;KEENAN, L
本文用脑干薄片标本研究了乙醇对中脑中缝背核（DR）中子的影响。低剂量乙醇（100 mg%和200 mg%）对DR细胞的兴奋作用大于抑制作用。较高剂量的乙醇在大多数DR神经元中产生抑制。目前的数据表明，乙醇的影响是双相的，低浓度倾向于兴奋和高浓度抑制DR神经元。
The effects of ethanol on midbrain dorsal raphe (DR) neutrons were studied using the brainstem slice preparations. Ethanol in low doses (100 mg% and 200 mg%) exerted more excitation than inhibition on DR cells. Higher doses of ethanol produced inhibition in the majority of DR neurons. The present data indicate that the effects of ethanol were biphasic with low concentrations tending to excite and high concentrations to inhibit DR neurons.