Autonomic cardiovascular reflexes in pregnancy. A longitudinal study.
Autonomic cardiovascular reflexes in pregnancy. A longitudinal study.
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DOI：
10.1007/bf01826181
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发表时间：
1994-08-01
期刊：
影响因子：
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通讯作者：
Antila, K J
中科院分区：
文献类型：
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作者：
Ekholm, E M;Piha, S J;Antila, K J
对22名健康妇女在怀孕前、怀孕三个月和分娩后的心血管反射进行了研究，以评价怀孕对血流动力学自主控制的影响。采用Valsalva动作、深呼吸试验、立位试验和等长握力试验评估自主神经功能的变化。我们发现怀孕改变了Valsalva动作，深呼吸试验和直立试验中的心率反应。深呼吸差（p = 0.03）和最大/最小比值（p = 0.03）在妊娠期降低，而站立心率增加（p < 0.0001）。妊娠期站立后收缩压和舒张压均升高。等长收缩运动的循环反应不受妊娠的影响。结果表明，副交感神经反应性在怀孕期间降低，分娩后恢复正常。
Cardiovascular reflexes were studied in 22 healthy women before they were pregnant, once during each pregnancy trimester and after delivery to evaluate the effect of pregnancy on autonomic control of haemodynamics. The Valsalva manoeuvre, the deep breathing test, the orthostatic test and the isometric handgrip test were used to assess changes in autonomic nervous function. We found that pregnancy altered the heart rate response in the Valsalva manoeuvre, the deep breathing test and the orthostatic tests. The deep breathing difference (p = 0.03) and max/min ratio (p = 0.03) decreased in pregnancy, whereas standing heart rate increased (p < 0.0001). Both the systolic and diastolic blood pressure increased after standing up during pregnancy. The circulatory responses to isometric exercise were not affected by pregnancy. The results show that parasympathetic responsiveness is decreased in pregnancy and that it returns to normal after delivery.