Paraneoplastic Cerebellar Ataxia and the Paraneoplastic Syndromes
Paraneoplastic Cerebellar Ataxia and the Paraneoplastic Syndromes
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副肿瘤性小脑共济失调和副肿瘤综合征
DOI：
10.1080/08998280.2015.11929234
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发表时间：
2015
影响因子：
--
通讯作者：
S. Shamim
中科院分区：
文献类型：
--
作者：
Sadaf Afzal;M. Recio;S. Shamim
副肿瘤性小脑共济失调，也称为副肿瘤性小脑变性，是一种广泛的副肿瘤性神经综合征，其神经症状是由潜在的恶性肿瘤间接引起的，最常见的是妇科、乳腺癌、肺癌或霍奇金淋巴瘤。我们描述一个严重的小脑功能障碍的患者归因于副肿瘤神经综合征。该病例强调了寻找副肿瘤综合征的必要性--既要在可治疗的阶段及早发现恶性肿瘤，又要像我们的病例一样，解决非常令人痛苦的症状，即使恶性肿瘤无法治愈，也要缓解患者的痛苦。
Paraneoplastic cerebellar ataxia, also known as paraneoplastic cerebellar degeneration, is one of the wide array of paraneoplastic neurological syndromes in which neurological symptoms are indirectly caused by an underlying malignancy, most commonly gynecological, breast, or lung cancer or Hodgkin's lymphoma. We describe a patient with severe cerebellar dysfunction attributed to a paraneoplastic neurological syndrome. The case highlights the need to look for paraneoplastic syndromes—both to discover malignancies early, at a treatable stage, and, as in our case, to address very distressing symptoms for the patient's relief even if the malignancy is not curable.