Molecular and genomic data identify the closest living relative of primates
Molecular and genomic data identify the closest living relative of primates
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DOI：
10.1126/science.1147555
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发表时间：
2007-11-02
期刊：
影响因子：
56.9
通讯作者：
Murphy, William J.
中科院分区：
文献类型：
--
作者：
Janecka, Jan E.;Miller, Webb;Murphy, William J.
要充分了解灵长类的形态和基因组进化，需要确定它们最接近的在世亲属。为了解决灵长类及其近亲之间的祖先关系，我们在包括灵长目、皮翅目(毛翅目)和斯堪的亚目(树懒目)在内的超目类群Euarchonta中寻找具有系统发育信息的稀有基因组变化的多物种基因组比对。我们还根据14个碱基的核基因构建了来自大多数主要灵长类谱系的代表的系统发育树，包括现存的猫和多种树栖动物，包括Ptilocercus lowii，Ptilocercus lowii。包括Ptilocercus在内的一项宽松的分子时钟分析表明，树龙大约出现在6300万年前。我们的数据表明，眼镜蛇是灵长类动物中现存的最近的近亲，表明它们的分化发生在白垩纪。
A full understanding of primate morphological and genomic evolution requires the identification of their closest living relative. In order to resolve the ancestral relationships among primates and their closest relatives, we searched multispecies genome alignments for phylogenetically informative rare genomic changes within the superordinal group Euarchonta, which includes the orders Primates, Dermoptera (colugos), and Scandentia (treeshrews). We also constructed phylogenetic trees from 14 kilobases of nuclear genes for representatives from most major primate lineages, both extant colugos, and multiple treeshrews, including the pentail treeshrew, Ptilocercus lowii, the only living member of the family Ptilocercidae. A relaxed molecular clock analysis including Ptilocercus suggests that treeshrews arose approximately 63 million years ago. Our data show that colugos are the closest living relatives of primates and indicate that their divergence occurred in the Cretaceous.