A genomic island provides Acidithiobacillus ferrooxidans ATCC 53993 additional copper resistance: a possible competitive advantage
A genomic island provides Acidithiobacillus ferrooxidans ATCC 53993 additional copper resistance: a possible competitive advantage
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DOI：
10.1007/s00253-011-3494-x
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发表时间：
2011-11-01
影响因子：
5
通讯作者：
Jerez, Carlos A.
中科院分区：
文献类型：
--
作者：
Orellana, Luis H.;Jerez, Carlos A.
有极大的兴趣了解极端嗜生物采矿细菌如何适应异常高浓度的铜在其环境中。嗜酸氧化亚铁硫杆菌ATCC 53993基因组具有与菌株ATCC 23270相同的铜抗性决定簇。然而，前一种菌株在其基因组中含有160-kb的基因组岛（GI），其在ATCC 23270中不存在。除了其他基因之外，该GI还包含编码另外的推定铜ATP酶和Cus系统的几个基因。A. ferrooxidans ATCC 53993对CuSO 4（>100 mM）的抗性比菌株ATCC 23270（
There is great interest in understanding how extremophilic biomining bacteria adapt to exceptionally high copper concentrations in their environment. Acidithiobacillus ferrooxidans ATCC 53993 genome possesses the same copper resistance determinants as strain ATCC 23270. However, the former strain contains in its genome a 160-kb genomic island (GI), which is absent in ATCC 23270. This GI contains, amongst other genes, several genes coding for an additional putative copper ATPase and a Cus system. A. ferrooxidans ATCC 53993 showed a much higher resistance to CuSO4 (>100 mM) than that of strain ATCC 23270 (