Homeostatic behavior of fast Fourier transform power in very low frequency non-rapid eye movement human electroencephalogram
Homeostatic behavior of fast Fourier transform power in very low frequency non-rapid eye movement human electroencephalogram
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DOI：
10.1016/j.neuroscience.2006.03.005
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发表时间：
2006-01-01
期刊：
影响因子：
3.3
通讯作者：
Feinberg, I.
中科院分区：
文献类型：
--
作者：
Campbell, I. G.;Higgins, L. M.;Feinberg, I.
基础研究表明，非快速眼动（NREM）睡眠的极低频（< 1 Hz）脑电图（EEG）波的生理和分子机制不同于较高（1-4 Hz）δ频率的EEG波。人类研究表明，极低频和1-4 Hz EEG的跨NREM周期动力学也不同。这些差异和报道的极低频EEG功率在一夜完全睡眠剥夺后增加的失败提出了一个问题，即极低频EEG是否显示出为较高δ频率建立的其他稳态特性。在这里，我们测试了非常低频率的EEG功率密度与正常一天中先前清醒持续时间的关系，以及这些低频是否符合稳态睡眠EEG的另一个标准：在午睡后期和午睡后睡眠中的功率守恒。对19名年轻人的数据进行了分析，这些数据记录在基线、白天小睡和午睡后睡眠的四个独立阶段。当午睡在一天的晚些时候进行时（即在较长的清醒持续时间之前），极低频NREM EEG中的功率密度线性增加。在18：00午睡后的夜晚，极低频功率减少了大约午睡中的功率量。因此，极低频EEG满足两个主要的稳态标准。我们假设，这些低频反映了非快速眼动睡眠逆转清醒大脑活动影响的执行过程，而不是功能过程。(c)2006年IBRO。由爱思唯尔有限公司出版。保留所有权利。
Basic research shows that the physiological and molecular mechanisms of very low frequency (< 1 Hz) electroencephalogram (EEG) waves of non-rapid eye movement (NREM) sleep differ from those of the higher (1-4 Hz) delta frequencies. Human studies show that the across-NREM period dynamics of very low frequency and 1-4 Hz EEG also differ. These differences and the reported failure of very low frequency EEG power to increase after a night of total sleep deprivation raise the question of whether very low frequency EEG shows the other homeostatic properties established for higher delta frequencies. Here we tested the relation of very low frequency EEG power density to prior waking duration across a normal day and whether these low frequencies meet another criterion for homeostatic sleep EEG: conservation of power across a late nap and post-nap sleep. Data from 19 young adults recorded in four separate sessions of baseline, daytime nap and post-nap sleep were analyzed. Power density in very low frequency NREM EEG increased linearly when naps were taken later in the day (i.e. were preceded by longer waking durations). In the night following an 18:00 h nap, very low frequency power was reduced by roughly the amount of power in the nap. Thus, very low frequency EEG meets two major homeostatic criteria. We hypothesize that these low frequencies reflect the executive rather than the functional processes by which NREM sleep reverses the effects of waking brain activity. (c) 2006 IBRO. Published by Elsevier Ltd. All rights reserved.