Cryptocin, a potent tetramic acid antimycotic from the endophytic fungus Cryptosporiopsis cf. quercina
Cryptocin, a potent tetramic acid antimycotic from the endophytic fungus Cryptosporiopsis cf. quercina
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DOI：
10.1021/ol000008d
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发表时间：
2000-03-23
期刊：
影响因子：
5.2
通讯作者：
Clardy, J
中科院分区：
文献类型：
--
作者：
Li, JY;Strobel, G;Clardy, J
隐孢子菌(Cryptosporiopsis)。栎属在培养过程中产生隐孢素，在其他真菌中，这种独特的四酸对稻瘟病的病原菌稻瘟病菌具有抗真菌活性，隐孢素对多种植物病原真菌也有活性，但对人类病原真菌不具有活性，隐孢子素的菱形晶体使X射线结晶学能够确定其结构，并简要讨论了隐孢素在栎属与寄主共生关系中的重要性。
The endophytic fungus Cryptosporiopsis of. quercina produces cryptocin in culture, Among other fungi, this unique tetramic acid displays antimycotic activity against Pyricularia oryzae, the causal agent of rice blast disease, Cryptocin also possesses activity against a wide variety of plant pathogenic but not human pathogenic fungi, The fine rhomboid-like crystals of cryptocin allowed structural elucidation by X-ray crystallography, The importance of cryptocin to the symbiotic relationship of C, quercina to its hosts is briefly discussed.