Biopharmaceutics and clinical pharmacokinetics: An introduction
Biopharmaceutics and clinical pharmacokinetics: An introduction
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生物药剂学和临床药代动力学：简介
DOI：
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发表时间：
1980
期刊：
影响因子：
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通讯作者：
R. Notari
中科院分区：
文献类型：
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作者：
R. Notari
引言参考速率、速率常数、和顺序顺序速率和速率常数主动和被动转运介绍被动转运主动转运参考药代动力学介绍药物处置常数-速率静脉输注房室模型及其局限性吸收速率常数参考文献生物药剂学血管外给药药物从胃肠道的吸收影响生物利用度的因素单次给药以延长给药时间参考文献给药方案介绍重复给药过程中的蓄积肾衰竭给药方案的调整多次给药恒定-药物设计和治疗中结构修饰的药代动力学方面抗菌剂前药的药代动力学立体异构体参考药代动力学在临床实践中的应用药代动力学药物相互作用临床药动
Introduction References Rates, Rate Constants, and Order Order Rates and Rate Constants Active and Passive Transport Introduction Passive Transport Active Transport References Pharmacokinetics Introduction Drug Disposition Constant-Rate Intravenous Infusion Compartmental Models and Their Limitations Absorption Rate Constants References Biopharmaceutics Extravascular Administration Absorption of Drugs from the Gastrointestinal Tract Factors Influencing Bioavailability Evaluation of the Bioavailability of a Single Drug Drug Delivery to Prolong Duration References Dosage Regimens Introduction Accumulation During Repetitive Dosing Adjustment of Dosage Regimen in Renal Failure Multiple Dosing of Constant-Rate Intravenous Infusions References Pharmacokinetic Aspects of Structural Modifications in Drug Design and Therapy Introduction Antimicrobial Agents Pharmacokinetics of Prodrugs Stereoisomers References Pharmacokinetic Applications in Clinical Practice Introduction Pharmacokinetic Drug Interactions Clinical Pharmacokinetics