The importance of repeat testing in detecting coronavirus disease 2019 (COVID-19) in a coronary artery bypass grafting patient

The importance of repeat testing in detecting coronavirus disease 2019 (COVID-19) in a coronary artery bypass grafting patient
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DOI:
10.1111/jocs.14604
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发表时间:
2020-05-12
影响因子:
1.6
通讯作者:
Kilic, Arman
Kilic, Arman
中科院分区:
医学4区
文献类型:
--
作者:
Fisher, Bryant;Seese, Laura;Kilic, Arman

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虽然择期心脏手术已被推迟,以防止2019冠状病毒病(COVID-19)传播并减少资源使用,但有紧急指征需要手术的患者在术后恢复期间仍可能面临感染疾病的风险。我们报告了一例81岁女性患者,她接受了紧急冠状动脉旁路移植术,并在出院后因COVID-19病例聚集而再次入院。尽管放射学和影像学关注COVID-19,但两次初始逆转录聚合酶链反应(RT-PCR)检测均为阴性,但第三次检测为阳性。该病例强调了COVID-19时代出院地点的风险,以及临床怀疑的重要性,对那些假定阳性的人进行早期隔离,并考虑到可用的COVID-19 RT-PCR的边缘敏感性进行重复检测。
While elective cardiac surgeries have been postponed to prevent coronavirus disease 2019 (COVID-19) transmission and to reduce resource utilization, patients with urgent indications necessitating surgery may still be at risk of contracting the disease throughout their postoperative recovery. We present a case of an 81-year-old female who underwent urgent coronary artery bypass grafting and was readmitted following discharge to a nursing facility with a cluster of COVID-19 cases. Despite symptomatology and imaging concerning for COVID-19, two initial reverse transcription polymerase chain reaction (RT-PCR) tests were negative but a third test was positive. This case emphasizes the risks of discharge location in the COVID-19 era as well as the importance of clinical suspicion, early isolation practices for those presumed positive, and repeat testing, given the marginal sensitivity of available COVID-19 RT-PCR.