Preparation and ESCA characterization of poly(vinyl chloride) surface-grafted with heparin-complexing poly(amido amine) chains.

Preparation and ESCA characterization of poly(vinyl chloride) surface-grafted with heparin-complexing poly(amido amine) chains.
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DOI:
10.1016/0142-9612(82)90058-8
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发表时间:
1982
期刊:
影响因子:
14
通讯作者:
P. Ferruti;R. Barbucci;N. Danzo;A. Torrisi;O. Puglisi;S. Pignataro;P. Spartano
P. Ferruti;R. Barbucci;N. Danzo;A. Torrisi;O. Puglisi;S. Pignataro;P. Spartano
中科院分区:
工程技术1区
文献类型:
--
作者:
P. Ferruti;R. Barbucci;N. Danzo;A. Torrisi;O. Puglisi;S. Pignataro;P. Spartano

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通过一种简单的方法,在聚氯乙烯表面接枝了聚酰胺-胺链。接枝的聚氯乙烯能够吸附肝素,从而提供潜在的非血栓形成表面。用ESCA研究了聚氨基胺的接枝及其对肝素的吸附。结果表明,接枝聚氨基胺的总量与接枝反应中使用的聚氨基胺的相对分子质量有关,而肝素在接枝材料上的吸附量与聚氨基胺的接枝链长无关。
By a simple process poly(amido-amine) chains have been grafted on the surface of poly(vinyl chloride). Grafted poly(vinyl chloride) is able to adsorb heparin, thus providing potentially non-thrombogenic surfaces. The grafting of poly(amido-amine), and the heparin adsorption have been studied by ESCA. It has been found that the total amount of grafted poly(amido-amine) depends on the molecular weight of the poly(amido-amine) used in the grafting reaction, but the amount of heparin adsorbed on the grafted material is relatively independent of the length of the poly(amido-amine) grafted chains.