BLOOD-COAGULATION STUDIES IN DOMESTIC PIGS (HANOVER BREED) AND MINIPIGS (GOETTINGEN BREED)
BLOOD-COAGULATION STUDIES IN DOMESTIC PIGS (HANOVER BREED) AND MINIPIGS (GOETTINGEN BREED)
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DOI：
10.1258/002367783781062262
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发表时间：
1983-01-01
影响因子：
2.4
通讯作者：
HOLTZ, WH
中科院分区：
文献类型：
--
作者：
KOSTERING, H;MAST, WP;HOLTZ, WH
对 60 头准备屠宰的汉诺威家猪和总共 84 头哥廷根小型猪进行了凝血研究。在这些猪中发现了高凝倾向，表现为PTT（部分凝血活酶时间）缩短、血栓弹力图中的r-和k-时间以及纤溶酶原和纤溶酶水平略有降低。许多价值观与人类相似。凝血酶时间较长。这可能更多是由于纤维蛋白降解产物（抗凝血酶 VI）的形成增强，而不是释放更多的内源性肝素。较长的爬行动物酶和凝血酶凝固酶时间支持了这一点。血小板计数仅略有不同。哥廷根小型猪和汉诺威家猪是比较凝血研究的合适动物。
Blood coagulation studies were performed on 60 Hanover domestic pigs ready for slaughter and a total of 84 Goettingen minipigs. A tendency to hypercoagulability was found in these pigs, expressed in a shortened PTT [partial thromboplastin time], r- and k-time in the thromboelastogram and a slightly reduced plasminogen and plasmin level. Many values were similar to those of man. Thrombin time was longer. This may be due more to enhanced formation of fibrin degradation products (antithrombin VI) than to greater amounts of endogenous heparin being released. The longer reptilase and thrombin coagulase times support this. The thrombocyte count differed only slightly. The Goettingen minipig and Hanover domestic pig are suitable animals for comparative blood coagulation studies.