Mechanisms behind estrogen's beneficial effect on muscle strength in females.
Mechanisms behind estrogen's beneficial effect on muscle strength in females.
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DOI：
10.1097/jes.0b013e3181d496bc
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发表时间：
2010-04
影响因子：
5.7
通讯作者：
Greising SM
中科院分区：
文献类型：
--
作者：
Lowe DA;Baltgalvis KA;Greising SM
当男性的血清睾丸素随着年龄的增长而下降时，肌肉会变得虚弱。睾丸激素的女性对应物雌激素也与年龄相关的力量丧失有关，但这些结果并不那么具有说服力。我们的工作假设是，雌激素确实有助于肌肉力量，其潜在机制涉及雌激素受体更多地改善肌肉质量，而不是数量。
Muscle weakness ensues when serum testosterone declines with age in men. Testosterone’s female counterpart, estrogen, has also been implicated in age-related strength loss but these results are less conclusive. Our working hypothesis is that estrogens do benefit muscle strength, and that the underlying mechanism involves estrogen receptors to improve muscle quality more so than quantity.