MAXIMUM ACTIVITIES, PROPERTIES AND DISTRIBUTION OF 5’NUCLEOTIDASE, ADENOSINE KINASE AND ADENOSINE DEAMINASE IN RAT AND HUMAN BRAIN
MAXIMUM ACTIVITIES, PROPERTIES AND DISTRIBUTION OF 5’NUCLEOTIDASE, ADENOSINE KINASE AND ADENOSINE DEAMINASE IN RAT AND HUMAN BRAIN
复制标题
大鼠和人脑中 5 核苷酸酶、腺苷激酶和腺苷脱氨酶的最大活性、性质和分布
DOI：
10.1111/j.1471-4159.1979.tb05187.x
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发表时间：
1979
影响因子：
4.7
通讯作者：
E. Newsholme
中科院分区：
文献类型：
--
作者：
E. Phillips;E. Newsholme
翻译后摘要-5 '核苷酸酶，腺苷激酶和腺苷脱氨酶的最大活动已被测定在大鼠和人脑的几个领域。大鼠脑和人脑的核苷酸酶和激酶活性无显著差异，但人脑的脱氨酶活性明显高于人脑。除人后脑腺苷脱氨酶活性较低外，大鼠脑的三个脑区和人脑的九个脑区的腺苷脱氨酶活性相似。这种变化可能表明在大脑的某些区域存在不同的腺苷稳态浓度。
Abstract— The maximum activities of 5’nucleotidase, adenosine kinase and adenosine deaminase have been measured in several areas of rat and human brain. There is no major difference between the activities of nucleotidase and kinase between rat and human brain, but the activity of deaminase is considerably higher in human brain. The activities of all these enzymes are similar in three areas of rat brain and nine areas of human brain, except for hind brain of the human, which has a low activity of adenosine deaminase. This variation may indicate the existence of different steady‐state concentrations of adenosine in certain areas of the brain.